Lipidomics studies on macrophages - bone marrow-derived macrophages treated with Kdo2-Lipid A and ATP
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Averages of biological replicates - (FA) Eicosanoids [media]
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: View time course graphs for averages of biological replicates| Details | Time course graph (ave of biol. reps) | LM_ID | Name | Mass (neutral) |
Kdo+ATP ATP Kdo Ctrl 0 hrs |
Kdo+ATP ATP Kdo Ctrl 15 min |
Kdo+ATP ATP Kdo Ctrl 30 min |
Kdo+ATP ATP Kdo Ctrl 1 hr |
Kdo+ATP ATP Kdo Ctrl 2 hrs |
Kdo+ATP ATP Kdo Ctrl 4 hrs |
Kdo+ATP ATP Kdo Ctrl 8 hrs |
Kdo+ATP ATP Kdo Ctrl 20 hrs | Units . . . . |
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Legend:
 :Ctrl
 :Kdo2-lipid A
 :ATP
 :ATP+Kdo2-lipid A
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LMFA04000027 | 10-HDoHE | 344.2 (ions) | - - - 0.011 |
0.016 0.01 0.012 0.012 |
0.013 0.011 0.013 0.012 |
0.015 0.011 0.011 0.01 |
0.019 0.013 0.011 0.01 |
0.022 0.012 0.012 0.009 |
0.019 0.01 0.011 0.011 |
0.021 0.009 0.008 0.013 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03050008 | 11,12-diHETrE | 338.2 (ions) | - - - 0.009 |
0.027 0.025 0.023 0.03 |
0.027 0.019 0.019 0.024 |
0.021 0.018 0.021 0.022 |
0.026 0.016 0.02 0.024 |
0.029 0.02 0.018 0.019 |
0.04 0.016 0.022 0.02 |
0.044 0.009 0.016 0.017 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03010060 | 11beta-PGE2 | 352.2 (ions) | - - - 0.046 |
0.168 0.052 0.042 0.077 |
0.231 0.032 0.031 0.059 |
0.262 0.025 0.034 0.058 |
0.34 0.031 0.044 0.032 |
0.656 0.381 0.072 0.055 |
0.821 0.535 0.121 0.036 |
1.98 1.23 0.179 0.048 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA04000028 | 11-HDoHE | 344.2 (ions) | - - - 0.022 |
0.026 0.022 0.021 0.027 |
0.023 0.025 0.02 0.022 |
0.033 0.022 0.022 0.019 |
0.029 0.021 0.02 0.02 |
0.035 0.021 0.022 0.021 |
0.032 0.02 0.019 0.023 |
0.041 0.02 0.016 0.027 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03060085 | 11-HETE | 320.2 (ions) | - - - 0.062 |
4.86 0.946 0.972 1.64 |
9.96 1.09 1.23 1.3 |
7.81 1.16 1.24 1.34 |
8.62 0.991 1.18 1.33 |
12.3 6.64 1.52 1.13 |
6.31 4.07 1.18 1.17 |
4.54 2.5 0.597 1.67 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03020022 | 11t LTE4 | 439.2 (ions) | - - - 0.003 |
0.014 0.003 0.003 0.002 |
0.027 0.01 0.003 0.003 |
0.029 0.02 0.004 0.003 |
0.026 0.019 0.003 0.004 |
0.029 0.019 0.003 0.003 |
0.027 0.021 0.003 0.004 |
0.03 0.016 0.004 0.004 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA01050351 | 12,13 diHOME | 314.2 (ions) | - - - 0.013 |
0.018 0.014 0.021 0.013 |
0.02 0.017 0.015 0.014 |
0.02 0.018 0.012 0.015 |
0.023 0.02 0.018 0.02 |
0.018 0.015 0.016 0.016 |
0.019 0.015 0.014 0.021 |
0.019 0.012 0.01 0.012 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03020015 | 12-epi-LTB4 | 336.2 (ions) | - - - 0.008 |
0.012 0.006 0.005 0.005 |
0.022 0.011 0.005 0.005 |
0.017 0.014 0.006 0.005 |
0.022 0.015 0.005 0.005 |
0.021 0.013 0.006 0.005 |
0.018 0.013 0.004 0.004 |
0.016 0.006 0.005 0.004 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03060088 | 12-HETE | 320.2 (ions) | - - - 0.439 |
0.318 0.265 0.255 0.3 |
0.361 0.32 0.289 0.328 |
0.569 0.482 0.431 0.452 |
0.556 0.338 0.355 0.427 |
0.383 0.22 0.192 0.248 |
0.306 0.128 0.132 0.135 |
0.18 0.097 0.033 0.092 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03070008 | 12S-HEPE | 318.2 (ions) | - - - 0.02 |
0.028 0.023 0.023 0.023 |
0.022 0.027 0.024 0.024 |
0.042 0.034 0.028 0.028 |
0.039 0.023 0.026 0.029 |
0.034 0.02 0.017 0.017 |
0.042 0.022 0.017 0.017 |
0.073 0.024 0.007 0.021 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03050002 | 12S-HHTrE | 280.2 (ions) | - - - 2.03 |
3.14 1.42 1.6 1.66 |
4.13 1.64 1.4 1.86 |
5.3 2.1 2.13 2.19 |
5.38 1.59 1.9 2.32 |
6.77 2.78 1.2 1.6 |
5.57 2.31 0.935 1.21 |
6.2 0.75 0.144 0.269 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03010033 | 13,14-dihydro-15-keto-PGA2 | 334.2 (ions) | - - - - |
0.004 - - - |
0.018 - - 0.004 |
0.03 - 0.015 0.018 |
0.051 - - 0.007 |
0.111 0.025 - - |
0.093 0.097 - - |
0.173 0.084 0.216 - |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03010022 | 13,14-dihydro-15-keto-PGD2 | 352.2 (ions) | - - - 0.067 |
0.137 0.101 0.05 0.039 |
0.106 0.106 0.065 0.068 |
0.142 0.078 0.072 0.073 |
0.176 0.104 0.066 0.085 |
0.263 0.138 0.067 0.08 |
0.191 0.116 0.067 0.073 |
0.235 0.117 0.065 0.063 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA04000029 | 13-HDoHE | 344.2 (ions) | - - - 0.05 |
0.061 0.037 0.034 0.045 |
0.052 0.041 0.043 0.044 |
0.06 0.047 0.043 0.037 |
0.07 0.042 0.041 0.041 |
0.123 0.059 0.046 0.036 |
0.135 0.067 0.051 0.036 |
0.23 0.081 0.049 0.044 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA01050349 | 13-HODE | 296.2 (ions) | - - - 0.18 |
0.326 0.27 0.27 0.272 |
0.287 0.255 0.242 0.175 |
0.331 0.204 0.218 0.246 |
0.28 0.316 0.196 0.269 |
0.505 0.352 0.207 0.182 |
0.506 0.343 0.235 0.181 |
0.786 0.486 0.301 0.307 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA02000051 | 13-HOTrE | 294.2 (ions) | - - - 0.011 |
0.033 0.017 0.023 0.01 |
0.016 0.016 0.02 0.022 |
0.019 0.014 0.021 0.024 |
0.028 0.019 0.015 0.014 |
0.038 0.019 0.028 0.017 |
0.031 0.02 0.038 0.03 |
0.04 0.034 0.027 0.018 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA02000016 | 13-oxoODE | 294.2 (ions) | - - - 0.021 |
0.029 0.023 0.033 0.019 |
0.158 0.016 0.015 0.018 |
0.024 0.02 0.013 0.012 |
0.024 0.027 0.026 0.026 |
0.038 0.022 0.013 0.024 |
0.025 0.017 0.019 0.025 |
0.02 0.02 0.015 0.011 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA01050145 | 13(S)-HOTrE(gamma) | 294.2 (ions) | - - - 0.077 |
0.085 0.076 0.073 0.074 |
0.076 0.07 0.065 0.078 |
0.102 0.075 0.07 0.077 |
0.113 0.073 0.078 0.079 |
0.146 0.093 0.074 0.075 |
0.184 0.084 0.072 0.069 |
0.313 0.09 0.047 0.056 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03050010 | 14,15-diHETrE | 338.2 (ions) | - - - 0.04 |
0.044 0.034 0.033 0.034 |
0.04 0.031 0.034 0.04 |
0.045 0.034 0.035 0.034 |
0.05 0.036 0.037 0.038 |
0.051 0.038 0.038 0.036 |
0.056 0.038 0.038 0.035 |
0.069 0.043 0.036 0.036 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03080005 | 14,15-EET | 320.2 (ions) | - - - 0.036 |
0.117 0.045 0.037 0.037 |
0.133 0.053 0.04 0.041 |
0.167 0.062 0.042 0.041 |
0.199 0.065 0.047 0.039 |
0.348 0.115 0.046 0.036 |
0.214 0.097 0.046 0.036 |
0.209 0.085 0.027 0.054 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA04000030 | 14-HDoHE | 344.2 (ions) | - - - 0.084 |
0.105 0.083 0.099 0.097 |
0.092 0.09 0.08 0.091 |
0.139 0.087 0.094 0.085 |
0.155 0.084 0.108 0.095 |
0.162 0.095 0.112 0.089 |
0.176 0.086 0.131 0.082 |
0.22 0.114 0.096 0.099 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03010051 | 15-deoxy-delta-12,14-PGD2 | 334.2 (ions) | - - - 0.556 |
0.852 0.565 0.494 0.464 |
0.672 0.49 0.467 0.429 |
0.822 0.521 0.569 0.519 |
0.923 0.499 0.573 0.543 |
1.58 0.738 0.733 0.565 |
1.65 1.09 0.669 0.606 |
6.04 3.22 0.957 0.657 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03010021 | 15-deoxy-delta-12,14-PGJ2 | 316.2 (ions) | - - - 0.019 |
0.042 0.026 0.01 0.022 |
0.039 0.01 0.009 0.012 |
0.032 0.017 0.021 0.022 |
0.035 0.014 0.014 0.013 |
0.065 0.022 0.017 0.015 |
0.097 0.047 0.019 0.014 |
0.403 0.192 0.03 0.03 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03070032 | 15-HEPE | 318.2 (ions) | - - - 0.033 |
0.033 0.032 0.028 0.031 |
0.035 0.029 0.026 0.033 |
0.045 0.035 0.031 0.033 |
0.049 0.03 0.032 0.037 |
0.057 0.032 0.029 0.028 |
0.083 0.029 0.026 0.024 |
0.117 0.024 0.029 0.059 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03060087 | 15-HETE | 320.2 (ions) | - - - 0.025 |
0.069 0.028 0.024 0.023 |
0.086 0.031 0.024 0.031 |
0.111 0.036 0.027 0.026 |
0.125 0.043 0.028 0.028 |
0.217 0.069 0.031 0.025 |
0.14 0.064 0.028 0.02 |
0.126 0.051 0.016 0.037 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03050007 | 15-HETrE | 322.3 (ions) | - - - 0.126 |
0.167 0.124 0.105 0.116 |
0.157 0.123 0.117 0.115 |
0.199 0.131 0.118 0.104 |
0.232 0.166 0.119 0.114 |
0.357 0.176 0.117 0.1 |
0.318 0.157 0.129 0.097 |
0.394 0.181 0.099 0.113 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA04000031 | 16-HDoHE | 344.2 (ions) | - - - 0.069 |
0.092 0.064 0.06 0.071 |
0.075 0.069 0.073 0.068 |
0.085 0.068 0.066 0.06 |
0.089 0.064 0.069 0.066 |
0.108 0.075 0.072 0.064 |
0.109 0.077 0.074 0.062 |
0.135 0.078 0.079 0.072 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03060069 | 16R-HETE | 320.2 (ions) | - - - 0.015 |
0.036 0.04 0.028 0.04 |
0.02 0.041 0.036 0.034 |
0.037 0.027 0.021 0.024 |
0.055 0.034 0.034 0.038 |
0.058 0.041 0.028 0.024 |
0.047 0.03 0.019 0.025 |
0.035 0.038 0.054 0.034 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA04000032 | 17-HDoHE | 344.2 (ions) | - - - 0.087 |
0.097 0.077 0.065 0.075 |
0.095 0.074 0.081 0.082 |
0.111 0.08 0.076 0.071 |
0.127 0.078 0.084 0.079 |
0.148 0.084 0.079 0.072 |
0.144 0.075 0.084 0.063 |
0.17 0.077 0.063 0.07 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03060091 | 17-HETE | 320.2 (ions) | - - - 0.022 |
0.032 0.026 0.024 0.021 |
0.019 0.047 0.022 0.021 |
0.034 0.031 0.03 0.029 |
0.038 0.046 0.02 0.028 |
0.04 0.031 0.02 0.021 |
0.045 0.024 0.028 0.023 |
0.046 0.022 0.019 0.05 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03070033 | 18-HEPE | 318.2 (ions) | - - - 0.019 |
0.034 0.024 0.023 0.02 |
0.013 0.03 0.023 0.014 |
0.032 0.018 0.015 0.019 |
0.024 0.016 0.016 0.014 |
0.031 0.03 0.015 0.013 |
0.033 0.033 0.022 0.014 |
0.047 0.032 0.011 0.02 |
pmol/ug DNA |
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:Ctrl
:Kdo2-lipid A
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:ATP+Kdo2-lipid A
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LMFA03060092 | 18-HETE | 320.2 (ions) | - - - 0.192 |
0.456 0.269 0.212 0.304 |
0.162 0.29 0.213 0.283 |
0.326 0.271 0.2 0.285 |
0.32 0.303 0.208 0.196 |
0.384 0.283 0.206 0.311 |
0.369 0.238 0.293 0.204 |
0.429 0.241 0.154 0.304 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA04000043 | 19,20 DiHDPA | 362.2 (ions) | - - - 0.245 |
0.328 0.233 0.241 0.25 |
0.237 0.256 0.264 0.275 |
0.297 0.25 0.217 0.228 |
0.34 0.224 0.249 0.233 |
0.393 0.289 0.284 0.271 |
0.404 0.297 0.295 0.279 |
0.505 0.42 0.392 0.474 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
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:ATP+Kdo2-lipid A
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LMFA03060074 | 19-HETE | 320.2 (ions) | - - - 0.182 |
0.296 0.277 0.242 0.192 |
0.253 0.334 0.199 0.182 |
0.327 0.341 0.236 0.217 |
0.338 0.274 0.237 0.206 |
0.336 0.295 0.199 0.216 |
0.385 0.307 0.183 0.211 |
0.359 0.276 0.226 0.251 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA04000033 | 20-HDoHE | 344.2 (ions) | - - - 0.082 |
0.1 0.066 0.065 0.072 |
0.084 0.075 0.078 0.071 |
0.1 0.077 0.071 0.058 |
0.115 0.08 0.069 0.076 |
0.143 0.09 0.076 0.064 |
0.144 0.087 0.079 0.059 |
0.149 0.078 0.071 0.065 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03010011 | 2,3-dinor-11b-PGF2alpha | 326.2 (ions) | - - - 0.006 |
0.02 0.014 0.003 0.005 |
0.024 0.019 0.009 0.009 |
0.023 0.029 0.009 0.007 |
0.02 0.027 0.014 0.007 |
0.028 0.023 0.014 0.016 |
0.024 0.027 0.011 0.018 |
0.041 0.04 0.019 0.027 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA04000024 | 4-HDoHE | 344.2 (ions) | - - - 0.029 |
0.038 0.032 0.027 0.031 |
0.044 0.042 0.028 0.035 |
0.074 0.049 0.033 0.033 |
0.102 0.056 0.031 0.033 |
0.108 0.05 0.027 0.026 |
0.066 0.034 0.026 0.023 |
0.048 0.02 0.013 0.029 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03060010 | 5,15-diHETE | 336.2 (ions) | - - - 0.017 |
0.019 0.017 0.018 0.016 |
0.02 0.016 0.016 0.016 |
0.023 0.017 0.015 0.013 |
0.022 0.019 0.019 0.014 |
0.022 0.02 0.019 0.017 |
0.024 0.018 0.018 0.018 |
0.028 0.021 0.021 0.021 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03070027 | 5-HEPE | 318.2 (ions) | - - - 0.004 |
0.006 0.005 0.004 0.004 |
0.012 0.007 0.004 0.004 |
0.011 0.006 0.005 0.003 |
0.012 0.005 0.003 0.004 |
0.023 0.007 0.004 0.004 |
0.023 0.005 0.004 0.003 |
0.023 0.005 0.013 0.076 |
pmol/ug DNA |
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:Ctrl
:Kdo2-lipid A
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LMFA03060084 | 5-HETE | 320.2 (ions) | - - - 0.03 |
0.087 0.044 0.038 0.036 |
0.134 0.064 0.038 0.04 |
0.15 0.081 0.045 0.042 |
0.149 0.068 0.044 0.038 |
0.172 0.06 0.037 0.029 |
0.079 0.037 0.037 0.026 |
0.058 0.056 0.017 0.046 |
pmol/ug DNA |
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:Ctrl
:Kdo2-lipid A
:ATP
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LMFA03110011 | 5-iPF2alpha-VI | 354.2 (ions) | - - - 0.065 |
0.086 0.069 0.06 0.062 |
0.082 0.067 0.061 0.064 |
0.09 0.068 0.055 0.069 |
0.091 0.093 0.065 0.066 |
0.113 0.088 0.077 0.071 |
0.113 0.091 0.069 0.079 |
0.169 0.126 0.086 0.1 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03040003 | 5S,6S-Lipoxin A4 | 352.2 (ions) | - - - 0.039 |
0.038 0.031 0.027 0.037 |
0.038 0.024 0.029 0.035 |
0.037 0.028 0.022 0.028 |
0.044 0.03 0.029 0.042 |
0.048 0.035 0.027 0.036 |
0.041 0.035 0.025 0.035 |
0.06 0.037 0.046 0.05 |
pmol/ug DNA |
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Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
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LMFA03050005 | 5(S)-HETrE | 322.3 (ions) | - - - 0.004 |
0.028 0.007 0.003 0.004 |
0.05 0.014 0.004 0.005 |
0.044 0.02 0.004 0.005 |
0.04 0.018 0.004 0.004 |
0.048 0.014 0.003 0.003 |
0.014 0.006 0.004 0.003 |
0.007 0.003 0.001 0.003 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03020014 | 6-trans-12-epi-LTB4 | 336.2 (ions) | - - - 0.007 |
0.012 0.004 0.003 0.005 |
0.013 0.006 0.003 0.004 |
0.016 0.012 0.004 0.005 |
0.016 0.01 0.004 0.004 |
0.018 0.011 0.004 0.004 |
0.017 0.008 0.004 0.004 |
0.014 0.004 0.003 0.003 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03020013 | 6-trans-LTB4 | 336.2 (ions) | - - - 0.008 |
0.008 0.004 0.003 0.004 |
0.013 0.007 0.004 0.003 |
0.009 0.007 0.003 0.003 |
0.016 0.007 0.004 0.004 |
0.01 0.005 0.004 0.003 |
0.006 0.007 0.003 0.005 |
0.009 0.002 0.003 0.004 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA04000025 | 7-HDoHE | 344.2 (ions) | - - - 0.032 |
0.035 0.03 0.029 0.029 |
0.033 0.033 0.025 0.026 |
0.039 0.03 0.027 0.029 |
0.04 0.031 0.024 0.027 |
0.044 0.03 0.024 0.025 |
0.044 0.024 0.02 0.029 |
0.057 0.02 0.017 0.042 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03060050 | 8,15-diHETE | 336.2 (ions) | - - - 3.74 |
3.48 3.15 2.88 3.14 |
2.99 3.32 2.42 2.4 |
5.09 4.23 2.12 2.37 |
4.74 3.94 3.15 3.17 |
3.64 3.19 3.07 3.09 |
3.47 2.84 2.23 2.48 |
4.7 2.15 4.83 2.6 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03050006 | 8,9-DiHETrE | 338.2 (ions) | - - - 0.005 |
0.005 0.007 0.004 0.006 |
0.007 0.006 0.005 0.005 |
0.007 0.008 0.006 0.006 |
0.01 0.007 0.006 0.007 |
0.016 0.011 0.006 0.006 |
0.014 0.007 0.006 0.006 |
0.015 0.009 0.005 0.008 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA04000026 | 8-HDoHE | 344.2 (ions) | - - - 0.047 |
0.055 0.043 0.035 0.046 |
0.048 0.044 0.042 0.041 |
0.066 0.048 0.044 0.048 |
0.074 0.046 0.046 0.041 |
0.086 0.047 0.048 0.037 |
0.083 0.033 0.045 0.034 |
0.105 0.036 0.027 0.049 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03060086 | 8-HETE | 320.2 (ions) | - - - 0.038 |
0.042 0.037 0.037 0.034 |
0.039 0.039 0.033 0.033 |
0.048 0.04 0.039 0.04 |
0.055 0.038 0.04 0.04 |
0.065 0.036 0.03 0.035 |
0.051 0.027 0.03 0.029 |
0.063 0.068 0.018 0.059 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03050011 | 8-HETrE | 322.3 (ions) | - - - 0.005 |
0.007 0.005 0.006 0.006 |
0.007 0.006 0.005 0.006 |
0.011 0.007 0.006 0.006 |
0.012 0.006 0.007 0.006 |
0.018 0.008 0.007 0.004 |
0.013 0.005 0.006 0.005 |
0.012 0.006 0.004 0.007 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03110001 | 8-iso-PGF2alpha | 354.2 (ions) | - - - 0.02 |
0.014 0.02 0.014 0.015 |
0.014 0.019 0.011 0.01 |
0.018 0.014 0.008 0.007 |
0.022 0.036 0.014 0.012 |
0.033 0.025 0.012 0.013 |
0.033 0.022 0.017 0.013 |
0.034 0.03 0.015 0.025 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA01050278 | 9-HODE | 296.2 (ions) | - - - 0.023 |
0.024 0.022 0.038 0.018 |
0.053 0.019 0.019 0.025 |
0.032 0.026 0.027 0.01 |
0.05 0.058 0.042 0.034 |
0.088 0.051 0.046 0.016 |
0.058 0.037 0.039 0.032 |
0.056 0.016 0.026 0.027 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA02000024 | 9-HOTrE | 294.2 (ions) | - - - 0.005 |
0.007 0.004 0.006 0.005 |
0.006 0.006 0.004 0.003 |
0.007 0.005 0.008 0.004 |
0.007 0.004 0.007 0.005 |
0.007 0.005 0.006 0.005 |
0.005 0.004 0.008 0.004 |
0.008 0.007 0.006 0.005 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA01030001 | Arachidonic acid | 304.2 (ions) | - - - 96.2 |
160 124 82.2 98.3 |
286 152 79.7 73.9 |
489 233 82.6 105 |
504 180 104 66.4 |
537 187 73.6 58.7 |
213 91.2 96.9 49.2 |
144 96.2 38.5 128 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03010034 | bicyclo-PGE2 | 334.2 (ions) | - - - 0.029 |
0.031 0.028 0.025 0.027 |
0.026 0.026 0.028 0.025 |
0.032 0.025 0.024 0.025 |
0.032 0.023 0.025 0.025 |
0.034 0.027 0.025 0.026 |
0.04 0.031 0.024 0.026 |
0.071 0.031 0.021 0.027 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03020001 | LTB4 | 336.2 (ions) | - - - 0.004 |
0.015 0.004 0.003 0.004 |
0.024 0.008 0.003 0.004 |
0.024 0.014 0.002 0.004 |
0.022 0.012 0.003 0.003 |
0.024 0.01 0.003 0.003 |
0.012 0.005 0.003 0.004 |
0.007 0.003 0.003 0.003 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03010049 | PGD1 | 354.2 (ions) | - - - 0.385 |
0.444 0.317 0.324 0.347 |
0.671 0.306 0.318 0.341 |
0.433 0.313 0.305 0.338 |
0.48 0.317 0.291 0.357 |
0.481 0.342 0.297 0.371 |
0.487 0.342 0.324 0.346 |
0.551 0.382 0.333 0.32 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03010004 | PGD2 | 352.2 (ions) | - - - 0.04 |
2.37 0.05 0.074 0.038 |
2.47 0.066 0.082 0.035 |
2.47 0.051 0.09 0.033 |
2.82 0.067 0.125 0.041 |
6.28 1.77 0.336 0.034 |
5.65 5.16 0.377 0.052 |
4.96 2.68 0.404 0.061 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03010142 | PGD3 | 350.2 (ions) | - - - - |
- - - - |
- - - - |
- - - - |
- - - - |
- - - - |
- - - - |
- - - - |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03010134 | PGE1 | 354.2 (ions) | - - - 0.053 |
0.129 0.103 0.078 0.047 |
0.16 0.084 0.071 0.06 |
0.194 0.086 0.077 0.058 |
0.205 0.115 0.063 0.059 |
0.317 0.117 0.086 0.069 |
0.398 0.182 0.097 0.059 |
0.46 0.162 0.135 0.063 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03010003 | PGE2 | 352.2 (ions) | - - - 0.003 |
0.015 0.003 0.003 0.003 |
0.019 0.003 0.003 0.003 |
0.019 0.004 0.003 0.003 |
0.026 0.004 0.004 0.003 |
0.061 0.018 0.008 0.003 |
0.098 0.055 0.013 0.003 |
0.263 0.094 0.029 0.003 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03010135 | PGE3 | 350.2 (ions) | - - - - |
- - - - |
- - - - |
- - - - |
- - - - |
- - - - |
- - - - |
- - - - |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03010137 | PGF1a | 356.3 (ions) | - - - 0.035 |
0.104 0.06 0.056 0.058 |
0.141 0.076 0.045 0.064 |
0.108 0.064 0.072 0.055 |
0.103 0.142 0.068 0.068 |
0.15 0.078 0.091 0.085 |
0.17 0.084 0.086 0.081 |
0.275 0.126 0.061 0.082 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03010002 | PGF2a | 354.2 (ions) | - - - 0.026 |
0.037 0.025 0.025 0.03 |
0.038 0.026 0.022 0.027 |
0.051 0.024 0.026 0.026 |
0.057 0.027 0.026 0.029 |
0.075 0.038 0.033 0.027 |
0.071 0.045 0.028 0.027 |
0.135 0.061 0.035 0.032 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03010019 | PGJ2 | 334.2 (ions) | - - - 0.071 |
0.131 0.061 0.064 0.072 |
0.108 0.066 0.067 0.071 |
0.16 0.065 0.068 0.071 |
0.18 0.073 0.067 0.071 |
0.37 0.091 0.085 0.071 |
0.467 0.24 0.093 0.074 |
1.78 0.784 0.135 0.072 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA01050143 | Tetranor-12(R)-HETE | 266.2 (ions) | - - - 3.07 |
3.06 2.87 3.04 2.99 |
2.66 3 2.39 3.15 |
3.95 3.36 3.28 3.62 |
3.59 2.73 3.11 3.89 |
3.21 2.57 2.31 3.41 |
3.51 1.98 2.07 2.82 |
2.78 0.73 0.382 1.4 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03030002 | TxB2 | 370.2 (ions) | - - - 0.366 |
0.513 0.382 0.374 0.362 |
0.458 0.378 0.367 0.368 |
0.543 0.381 0.359 0.352 |
0.567 0.368 0.357 0.362 |
0.621 0.419 0.368 0.369 |
0.595 0.444 0.366 0.368 |
0.729 0.467 0.367 0.357 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
LMFA03030006 | TXB3 | 368.2 (ions) | - - - 0.146 |
0.249 0.18 0.217 0.224 |
2.27 0.137 0.272 0.19 |
0.207 0.081 0.199 0.097 |
0.105 0.138 0.147 0.228 |
0.161 0.111 0.157 0.129 |
0.121 0.096 0.167 0.104 |
0.105 0.054 0.124 0.122 |
pmol/ug DNA |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
- | DNA | - | - - - 10.6 |
9.6 9.86 10.1 9.53 |
11 10.9 9.3 11.2 |
7.65 9.19 9.94 9.52 |
7.47 7.96 8.5 11.1 |
6.3 9.33 12.5 11.5 |
8.41 9.99 8.94 11.4 |
7.71 10.9 12.7 11.9 |
ug/sample |
|
|
Legend:
:Ctrl
:Kdo2-lipid A
:ATP
:ATP+Kdo2-lipid A
|
- | TNF | - | - - - - |
237 0.946 194 - |
229 0.946 172 1.05 |
213 2.76 160 - |
241 56.4 176 - |
278 225 177 - |
222 186 168 1.18 |
240 215 155 1.18 |
pg/ml |