LMPD Database

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LMP012937

Record overview

LMPD IDLMP012937
Gene ID171118
SpeciesMacaca mulata (Rhesus monkey)
Gene Namecarboxylesterase 2C
Gene SymbolCes2c
SynonymsCes2; Ces2l; CESRL4;
Alternate namescarboxylesterase 2C; carboxylesterase 2 (intestine, liver);
Chromosome1
Map Location1q55
EC Number3.1.1.1
Summaryenzyme that is responsible for the hydrolysis of long-chain fatty acids and thioesters; may play a role in lipid metabolism and/or the detoxification of certain drugs [RGD, Feb 2006]
OrthologsView orthologs and multiple alignments for Ces2c

Proteins

carboxylesterase 2C precursor
Refseq ID:NP_598270
Protein GI:19424284
UniProt ID:O70631
mRNA ID:NM_133586
Length:561
RefSeq Status:
MARKQPHSWLNAVLFGLLLILIHVWGQDSPESSSIRTTHTGQVRGKLDHVRDTKAGVHTFLGIPFAKAPVGPLRFAPPEDPEPWSGVRDGTSHPAMCLQN
IDMLDEVGLTDMKMILSSIPMSEDCLYLNIYTPAHAHEGSNLPVMVCIHGGALVIGMASMCDGSLLAVNEDLVVVAIQYRLGVLGFFSTGDEHARGNWGY
LDQVAALRWVQQNIAHFGGNPNRVTIFGVSAGGTSVSSHVISPMSQGLFHGAIMESGVALLPDLISETSETVSTTVAKLSGCEATDSETLVRCLRAKSGA
EILVINKVFKMIPAVVDGEFLPRHPKELLASEDFRPVPSIIGVNTDEYCCTIPMVMGTAQIIKELSRENLQAVLKDTAAQMMLPPECGDLLMEEYMGNTD
DPQTLQIQYAEMMGDFLFVIPALQVAHFQRSHAPVYFYEFQHAPSYFKNVRPPHVKADHADEVPFVFGSFFWGIKVDFTEEEKLLSRRMMKYWANFARHG
NPNSEGLPYWPVLDHDEQYLQLDTQPAVDRALKARRLQFWTKTLPQKIQELNGAQKNHAEL
 

sig_peptide: 1..26
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3014
peptide sequence: 
MARKQPHSWLNAVLFGLLLILIHVWG

mat_peptide: 27..561
product: carboxylesterase 2C
note: lack the glycosylation motif; phenobarbital-inducible form
calculated_mol_wt: 59194
peptide sequence: 
QDSPESSSIRTTHTGQVRGKLDHVRDTKAGVHTFLGIPFAKAPVGPLRFAPPEDPEPWSGVRDGTSHPAMCLQNIDMLDEVGLTDMKMILSSIPMSEDCL
YLNIYTPAHAHEGSNLPVMVCIHGGALVIGMASMCDGSLLAVNEDLVVVAIQYRLGVLGFFSTGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPNRVTI
FGVSAGGTSVSSHVISPMSQGLFHGAIMESGVALLPDLISETSETVSTTVAKLSGCEATDSETLVRCLRAKSGAEILVINKVFKMIPAVVDGEFLPRHPK
ELLASEDFRPVPSIIGVNTDEYCCTIPMVMGTAQIIKELSRENLQAVLKDTAAQMMLPPECGDLLMEEYMGNTDDPQTLQIQYAEMMGDFLFVIPALQVA
HFQRSHAPVYFYEFQHAPSYFKNVRPPHVKADHADEVPFVFGSFFWGIKVDFTEEEKLLSRRMMKYWANFARHGNPNSEGLPYWPVLDHDEQYLQLDTQP
AVDRALKARRLQFWTKTLPQKIQELNGAQKNHAEL