LMPD Database

LMP009129

Gene Information

Entrez Gene ID42737
Gene Namehedgehog
Gene Symbolhh
SpeciesDrosophila melanogaster
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0016023 IDA:FlyBaseCcytoplasmic membrane-bounded vesicle
GO:0030139 IDA:FlyBaseCendocytic vesicle
GO:0005768 IDA:FlyBaseCendosome
GO:0005576 NAS:UniProtKBCextracellular region
GO:0005615 IDA:FlyBaseCextracellular space
GO:0005634 IDA:UniProtKBCnucleus
GO:0005886 NAS:UniProtKBCplasma membrane
GO:0016015 TAS:FlyBaseFmorphogen activity
GO:0005113 NAS:UniProtKBFpatched binding
GO:0008233 IEA:UniProtKB-KWFpeptidase activity
GO:0005119 NAS:UniProtKBFsmoothened binding
GO:0007487 TAS:FlyBasePanalia development
GO:0021960 IMP:FlyBasePanterior commissure morphogenesis
GO:0035288 TAS:FlyBasePanterior head segmentation
GO:0008595 NAS:FlyBasePanterior/posterior axis specification, embryo
GO:0048099 TAS:FlyBasePanterior/posterior lineage restriction, imaginal disc
GO:0001746 IMP:FlyBasePBolwig's organ morphogenesis
GO:0045168 IMP:UniProtKBPcell-cell signaling involved in cell fate commitment
GO:0007386 TAS:FlyBasePcompartment pattern specification
GO:0001745 TAS:FlyBasePcompound eye morphogenesis
GO:0001751 TAS:FlyBasePcompound eye photoreceptor cell differentiation
GO:0035231 IMP:FlyBasePcytoneme assembly
GO:0048066 TAS:FlyBasePdevelopmental pigmentation
GO:0007398 NAS:FlyBasePectoderm development
GO:0009880 IEP:UniProtKBPembryonic pattern specification
GO:0008544 TAS:FlyBasePepidermis development
GO:0007427 IMP:FlyBasePepithelial cell migration, open tracheal system
GO:0048592 IMP:FlyBasePeye morphogenesis
GO:0007440 TAS:FlyBasePforegut morphogenesis
GO:0035224 IEP:FlyBasePgenital disc anterior/posterior pattern formation
GO:0035215 IMP:FlyBasePgenital disc development
GO:0035232 TAS:FlyBasePgerm cell attraction
GO:0008354 IMP:FlyBasePgerm cell migration
GO:0042078 TAS:FlyBasePgerm-line stem cell division
GO:0008347 IMP:FlyBasePglial cell migration
GO:0007506 IMP:FlyBasePgonadal mesoderm development
GO:0040007 NAS:FlyBasePgrowth
GO:0007507 NAS:FlyBasePheart development
GO:0060914 IMP:FlyBasePheart formation
GO:0007442 IMP:FlyBasePhindgut morphogenesis
GO:0007474 TAS:FlyBasePimaginal disc-derived wing vein specification
GO:0007446 TAS:FlyBasePimaginal disc growth
GO:0007447 NAS:FlyBasePimaginal disc pattern formation
GO:0016539 IEA:InterProPintein-mediated protein splicing
GO:0035217 IMP:FlyBasePlabial disc development
GO:0007478 TAS:FlyBasePleg disc morphogenesis
GO:0007498 NAS:FlyBasePmesoderm development
GO:0016335 IMP:FlyBasePmorphogenesis of larval imaginal disc epithelium
GO:0031397 IDA:FlyBasePnegative regulation of protein ubiquitination
GO:0045861 IMP:FlyBasePnegative regulation of proteolysis
GO:0007424 TAS:FlyBasePopen tracheal system development
GO:0030707 TAS:FlyBasePovarian follicle cell development
GO:0030713 TAS:FlyBasePovarian follicle cell stalk formation
GO:0007280 IGI:FlyBasePpole cell migration
GO:0045743 IMP:FlyBasePpositive regulation of fibroblast growth factor receptor signaling pathway
GO:0007228 IGI:FlyBasePpositive regulation of hh target transcription factor activity
GO:0045880 TAS:FlyBasePpositive regulation of smoothened signaling pathway
GO:0042993 IMP:FlyBasePpositive regulation of transcription factor import into nucleus
GO:0035289 TAS:FlyBasePposterior head segmentation
GO:0007458 IMP:FlyBasePprogression of morphogenetic furrow involved in compound eye morphogenesis
GO:0016540 IDA:UniProtKBPprotein autoprocessing
GO:0045464 NAS:FlyBasePR8 cell fate specification
GO:0042127 NAS:FlyBasePregulation of cell proliferation
GO:2000274 IMP:FlyBasePregulation of epithelial cell migration, open tracheal system
GO:0007346 IMP:FlyBasePregulation of mitotic cell cycle
GO:0046620 TAS:FlyBasePregulation of organ growth
GO:0042306 IMP:FlyBasePregulation of protein import into nucleus
GO:0006357 TAS:FlyBasePregulation of transcription from RNA polymerase II promoter
GO:0007367 IEP:UniProtKBPsegment polarity determination
GO:0007224 IGI:FlyBasePsmoothened signaling pathway
GO:0048103 TAS:FlyBasePsomatic stem cell division
GO:0035277 IMP:FlyBasePspiracle morphogenesis, open tracheal system
GO:0035290 TAS:FlyBasePtrunk segmentation
GO:0007418 IMP:FlyBasePventral midline development
GO:0048100 TAS:FlyBasePwing disc anterior/posterior pattern formation
GO:0007473 TAS:FlyBasePwing disc proximal/distal pattern formation
KEGG Pathway Links
KEGG Pathway IDDescription
dme04340Hedgehog signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
6226522Class B/2 (Secretin family receptors)
6227054Release of Hh-Np from the secreting cell