LMPD Database

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LMP006528

Record overview

LMPD IDLMP006528
Gene ID83592
SpeciesHomo sapiens (Human)
Gene Namealdo-keto reductase family 1, member E2
Gene SymbolAKR1E2
SynonymsAKR1CL2; AKRDC1; LoopADR; hTSP; htAKR
Alternate names1,5-anhydro-D-fructose reductase; AF reductase; testis-specific protein; aldo-keto reductase loopADR; aldo-keto reductase family 1, member C-like 2; aldo-keto reductase family 1 member C-like protein 2
Chromosome10
Map Location10p15.1
EC Number1.1.1.263
SummaryThe protein encoded by this gene is a member of the aldo-keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD(P)H-dependent oxido-reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
OrthologsView orthologs and multiple alignments for AKR1E2

Proteins

1,5-anhydro-D-fructose reductase isoform 1
Refseq ID:NP_001035267
Protein GI:93277124
UniProt ID:Q96JD6
mRNA ID:NM_001040177
Length:320
RefSeq Status:REVIEWED
MGDIPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYL
IHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPY
LTQKNLISFCQSRDVSVTAYRPLGGSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNL
RLAMFPITKNHKDYPFHIEY
 
1,5-anhydro-D-fructose reductase isoform 2
Refseq ID:NP_001257950
Protein GI:402244307
UniProt ID:Q96JD6
mRNA ID:NM_001271021
Length:263
RefSeq Status:REVIEWED
MGDIPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYL
IHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQILIRFQ
IQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKNHKDYPFHIEY
 
1,5-anhydro-D-fructose reductase isoform 3
Refseq ID:NP_001257954
Protein GI:402478636
UniProt ID:Q96JD6
mRNA ID:NM_001271025
Length:222
RefSeq Status:REVIEWED
MGDIPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYL
IHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNR
NLRLAMFPITKNHKDYPFHIEY