LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP006421

Record overview

LMPD IDLMP006421
Gene ID5918
SpeciesHomo sapiens (Human)
Gene Nameretinoic acid receptor responder (tazarotene induced) 1
Gene SymbolRARRES1
SynonymsLXNL; TIG1
Alternate namesretinoic acid receptor responder protein 1; latexin-like; RAR-responsive protein TIG1; tazarotene-induced gene 1 protein
Chromosome3
Map Location3q25.32
SummaryThis gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for RARRES1

Proteins

retinoic acid receptor responder protein 1 isoform 1 precursor
Refseq ID:NP_996846
Protein GI:46255043
UniProt ID:P49788
mRNA ID:NM_206963
Length:294
RefSeq Status:REVIEWED
MQPRRQRLPAPWSGPRGPRPTAPLLALLLLLAPVAAPAGSGDPDDPGQPQDAGVPRRLLQQAARAALHFFNFRSGSPSALRVLAEVQEGRAWINPKEGCK
VHVVFSTERYNPESLLQEGEGRLGKCSARVFFKNQKPRPTINVTCTRLIEKKKRQQEDYLLYKQMKQLKNPLEIVSIPDNHGHIDPSLRLIWDLAFLGSS
YVMWEMTTQVSHYYLAQLTSVRQWKTNDDTIDFDYTVLLHELSTQEIIPCRIHLVWYPGKPLKVKYHCQELQTPEEASGTEEGSAVVPTELSNF
 
sig_peptide: 1..41
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 4252
peptide sequence: 
MQPRRQRLPAPWSGPRGPRPTAPLLALLLLLAPVAAPAGSG

sig_peptide: 1..41
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 4252
peptide sequence: 
MQPRRQRLPAPWSGPRGPRPTAPLLALLLLLAPVAAPAGSG
 
retinoic acid receptor responder protein 1 isoform 2 precursor
Refseq ID:NP_002879
Protein GI:46255041
UniProt ID:P49788
mRNA ID:NM_002888
Length:228
RefSeq Status:REVIEWED
MQPRRQRLPAPWSGPRGPRPTAPLLALLLLLAPVAAPAGSGDPDDPGQPQDAGVPRRLLQQAARAALHFFNFRSGSPSALRVLAEVQEGRAWINPKEGCK
VHVVFSTERYNPESLLQEGEGRLGKCSARVFFKNQKPRPTINVTCTRLIEKKKRQQEDYLLYKQMKQLKNPLEIVSIPDNHGHIDPSLRLIWDLAFLGSS
YVMWEMTTQVSHYYLAQLTSVRQWVRKT