LMPD Database

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LMP006247

Record overview

LMPD IDLMP006247
Gene ID93183
SpeciesHomo sapiens (Human)
Gene Namephosphatidylinositol glycan anchor biosynthesis, class M
Gene SymbolPIGM
SynonymsGPI-MT-I
Alternate namesGPI mannosyltransferase 1; GPI mannosyltransferase I; PIG-M mannosyltransferase; DPM:GlcN-(acyl-)PI mannosyltransferase; dol-P-Man dependent GPI mannosyltransferase; phosphatidylinositol-glycan biosynthesis class M protein
Chromosome1
Map Location1q23.2
EC Number2.4.1.-
SummaryThis gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI)-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a mannosyltransferase, GPI-MT-I, that transfers the first mannose to GPI on the lumenal side of the endoplasmic reticulum. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for PIGM

Proteins

GPI mannosyltransferase 1
Refseq ID:NP_660150
Protein GI:21553315
UniProt ID:Q9H3S5
mRNA ID:NM_145167
Length:423
RefSeq Status:REVIEWED
MGSTKHWGEWLLNLKVAPAGVFGVAFLARVALVFYGVFQDRTLHVRYTDIDYQVFTDAARFVTEGRSPYLRATYRYTPLLGWLLTPNIYLSELFGKFLFI
SCDLLTAFLLYRLLLLKGLGRRQACGYCVFWLLNPLPMAVSSRGNADSIVASLVLMVLYLIKKRLVACAAVFYGFAVHMKIYPVTYILPITLHLLPDRDN
DKSLRQFRYTFQACLYELLKRLCNRAVLLFVAVAGLTFFALSFGFYYEYGWEFLEHTYFYHLTRRDIRHNFSPYFYMLYLTAESKWSFSLGIAAFLPQLI
LLSAVSFAYYRDLVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMPWKRAVVLLMLWFIGQAMWLAPAYVLEFQGKNTFLFIWLAGLFFLLIN
CSILIQIISHYKEEPLTERIKYD