LMPD Database

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LMP006010

Record overview

LMPD IDLMP006010
Gene ID6583
SpeciesHomo sapiens (Human)
Gene Namesolute carrier family 22 (organic cation/zwitterion transporter), member 4
Gene SymbolSLC22A4
SynonymsOCTN1
Alternate namessolute carrier family 22 member 4; ET transporter; ergothioneine transporter; integral membrane transport protein; organic cation/carnitine transporter 1; solute carrier family 22 (organic cation/ergothioneine transporter), member 4
Chromosome5
Map Location5q31.1
SummaryPolyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is an organic cation transporter and plasma integral membrane protein containing eleven putative transmembrane domains as well as a nucleotide-binding site motif. Transport by this protein is at least partially ATP-dependent. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for SLC22A4

Proteins

solute carrier family 22 member 4
Refseq ID:NP_003050
Protein GI:24497490
UniProt ID:Q9H015
mRNA ID:NM_003059
Length:551
RefSeq Status:REVIEWED
MRDYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVPDAANLSSAWRNNSVPLRLRDGREVPHSCSRYRLATIANFSALGLEPG
RDVDLGQLEQESCLDGWEFSQDVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAVQTGFSFLQIFSISWEMFTVLF
VIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTFFAVGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQKA
AKMNNIAVPAVIFDSVEELNPLKQQKAFILDLFRTRNIAIMTIMSLLLWMLTSVGYFALSLDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYI
IAAVLFWGGGVLLFIQLVPVDYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVYLGAYNRMLPYIVMGSLTVLI
GILTLFFPESLGMTLPETLEQMQKVKWFRSGKKTRDSMETEENPKVLITAF