LMPD Database

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LMP005763

Record overview

LMPD IDLMP005763
Gene ID56052
SpeciesHomo sapiens (Human)
Gene NameALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
Gene SymbolALG1
SynonymsCDG1K; HMAT1; HMT-1; HMT1; MT-1; Mat-1; hMat-1
Alternate nameschitobiosyldiphosphodolichol beta-mannosyltransferase; mannosyltransferase-1; beta-1,4 mannosyltransferase; beta-1,4-mannosyltransferase; GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase; asparagine-linked glycosylation protein 1 homolog; GDP-mannose-dolichol diphosphochitobiose mannosyltransferase; asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog; asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase)
Chromosome16
Map Location16p13.3
EC Number2.4.1.142
SummaryThe enzyme encoded by this gene catalyzes the first mannosylation step in the biosynthesis of lipid-linked oligosaccharides. This gene is mutated in congenital disorder of glycosylation type Ik. [provided by RefSeq, Dec 2008]
OrthologsView orthologs and multiple alignments for ALG1

Proteins

chitobiosyldiphosphodolichol beta-mannosyltransferase
Refseq ID:NP_061982
Protein GI:41350216
UniProt ID:Q9BT22
mRNA ID:NM_019109
Length:464
RefSeq Status:REVIEWED
MAASCLVLLALCLLLPLLLLGGWKRWRRGRAARHVVAVVLGDVGRSPRMQYHALSLAMHGFSVTLLGFCNSKPHDELLQNNRIQIVGLTELQSLAVGPRV
FQYGVKVVLQAMYLLWKLMWREPGAYIFLQNPPGLPSIAVCWFVGCLCGSKLVIDWHNYGYSIMGLVHGPNHPLVLLAKWYEKFFGRLSHLNLCVTNAMR
EDLADNWHIRAVTVYDKPASFFKETPLDLQHRLFMKLGSMHSPFRARSEPEDPVTERSAFTERDAGSGLVTRLRERPALLVSSTSWTEDEDFSILLAALE
KFEQLTLDGHNLPSLVCVITGKGPLREYYSRLIHQKHFQHIQVCTPWLEAEDYPLLLGSADLGVCLHTSSSGLDLPMKVVDMFGCCLPVCAVNFKCLHEL
VKHEENGLVFEDSEELAAQLQMLFSNFPDPAGKLNQFRKNLRESQQLRWDESWVQTVLPLVMDT