LMPD Database

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LMP005727

Record overview

LMPD IDLMP005727
Gene ID130367
SpeciesHomo sapiens (Human)
Gene Namesphingosine-1-phosphate phosphatase 2
Gene SymbolSGPP2
SynonymsSPP2
Alternate namessphingosine-1-phosphate phosphatase 2; hSPP2; SPPase2; sphingosine-1-phosphatase 2; sphingosine-1-phosphate phosphotase 2; sphingosine 1-phosphate phosphohydrolase 2
Chromosome2
Map Location2q36.1
EC Number3.1.3.-
SummarySphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP2 catalyzes the degradation of S1P (Ogawa et al., 2003 [PubMed 12411432]).[supplied by OMIM, Jun 2009]
OrthologsView orthologs and multiple alignments for SGPP2

Proteins

sphingosine-1-phosphate phosphatase 2
Refseq ID:NP_689599
Protein GI:23510289
UniProt ID:Q8IWX5
mRNA ID:NM_152386
Length:399
RefSeq Status:PROVISIONAL
MAELLRSLQDSQLVARFQRRCGLFPAPDEGPRENGADPTERAARVPGVEHLPAANGKGGEAPANGLRRAAAPEAYVQKYVVKNYFYYYLFQFSAALGQEV
FYITFLPFTHWNIDPYLSRRLIIIWVLVMYIGQVAKDVLKWPRPSSPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLISTMDRYQYPFVLGLVMAVVFS
TLVCLSRLYTGMHTVLDVLGGVLITALLIVLTYPAWTFIDCLDSASPLFPVCVIVVPFFLCYNYPVSDYYSPTRADTTTILAAGAGVTIGFWINHFFQLV
SKPAESLPVIQNIPPLTTYMLVLGLTKFAVGIVLILLVRQLVQNLSLQVLYSWFKVVTRNKEARRRLEIEVPYKFVTYTSVGICATTFVPMLHRFLGLP