LMPD Database

LMP005381

Record overview

LMPD IDLMP005381
Gene ID55501
SpeciesHomo sapiens (Human)
Gene Namecarbohydrate (chondroitin 4) sulfotransferase 12
Gene SymbolCHST12
SynonymsC4S-2; C4ST-2; C4ST2
Alternate namescarbohydrate sulfotransferase 12; sulfotransferase Hlo; chondroitin 4-sulfotransferase 2; chondroitin 4-O-sulfotransferase 2
Chromosome7
Map Location7p22
EC Number2.8.2.5
SummaryThe protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. Alternatively spliced transcript variants differing only in their 5' UTRs have been found for this gene. [provided by RefSeq, Aug 2011]
OrthologsView orthologs and multiple alignments for CHST12

Proteins

carbohydrate sulfotransferase 12
Refseq ID:NP_001230723
Protein GI:345090972
UniProt ID:Q9NRB3
mRNA ID:NM_001243794
Length:414
RefSeq Status:REVIEWED
MTKARLFRLWLVLGSVFMILLIIVYWDSAGAAHFYLHTSFSRPHTGPPLPTPGPDRDRELTADSDVDEFLDKFLSAGVKQSDLPRKETEQPPAPGSMEES
VRGYDWSPRDARRSPDQGRQQAERRSVLRGFCANSSLAFPTKERAFDDIPNSELSHLIVDDRHGAIYCYVPKVACTNWKRVMIVLSGSLLHRGAPYRDPL
RIPREHVHNASAHLTFNKFWRRYGKLSRHLMKVKLKKYTKFLFVRDPFVRLISAFRSKFELENEEFYRKFAVPMLRLYANHTSLPASAREAFRAGLKVSF
ANFIQYLLDPHTEKLAPFNEHWRQVYRLCHPCQIDYDFVGKLETLDEDAAQLLQLLQVDRQLRFPPSYRNRTASSWEEDWFAKIPLAWRQQLYKLYEADF
VLFGYPKPENLLRD
 
carbohydrate sulfotransferase 12
Refseq ID:NP_001230724
Protein GI:345090974
UniProt ID:Q9NRB3
mRNA ID:NM_001243795
Length:414
RefSeq Status:REVIEWED
Protein sequence is identical to GI:345090972 (mRNA isoform)
 
carbohydrate sulfotransferase 12
Refseq ID:NP_061111
Protein GI:8922112
UniProt ID:Q9NRB3
mRNA ID:NM_018641
Length:414
RefSeq Status:REVIEWED
Protein sequence is identical to GI:345090972 (mRNA isoform)