LMPD Database

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LMP005147

UniProt Annotations

Entry Information
Gene Namecarboxylesterase 2C
Protein EntryEST2C_MOUSE
UniProt IDQ91WG0
SpeciesMouse
Comments
Comment typeDescription
Biophysicochemical PropertiesKinetic parameters: KM=98.8 uM for palmitoyl-dl-carnitine; KM=392 uM for p-nitrophenylacetate; Vmax=1.67 umol/min/mg enzyme with palmitoyl-dl-carnitine; Vmax=353 umol/min/mg enzyme with p-nitrophenylacetate;
Catalytic ActivityO-acylcarnitine + H(2)O = a fatty acid + L- carnitine. {ECO:0000269|PubMed:12859986}.
FunctionHydrolase with high activity towards palmitoylcarnitine. Is also active with p-nitrophenylacetate and alpha- naphthylacetate. {ECO:0000269|PubMed:12859986}.
InductionUp-regulated in liver by di-(2-ethylhexyl)phtalate (DEHP). {ECO:0000269|PubMed:12859986}.
SimilarityBelongs to the type-B carboxylesterase/lipase family. {ECO:0000305}.
Subcellular LocationMicrosome {ECO:0000269|PubMed:12859986}. Endoplasmic reticulum {ECO:0000305}.
Tissue SpecificityDetected in liver (at protein level). {ECO:0000269|PubMed:12859986}.