LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP004948

Record overview

LMPD IDLMP004948
Gene ID10690
SpeciesHomo sapiens (Human)
Gene Namefucosyltransferase 9 (alpha (1,3) fucosyltransferase)
Gene SymbolFUT9
SynonymsFuc-TIX
Alternate namesalpha-(1,3)-fucosyltransferase 9; fucT-IX; fucosyltransferase IX; galactoside 3-L-fucosyltransferase
Chromosome6
Map Location6q16
EC Number2.4.1.-
SummaryThe protein encoded by this gene belongs to the glycosyltransferase family. It is localized to the golgi, and catalyzes the last step in the biosynthesis of Lewis X (LeX) antigen, the addition of a fucose to precursor polysaccharides. This protein is one of the few fucosyltransferases that synthesizes the LeX oligosaccharide (CD15) expressed in the organ buds progressing in mesenchyma during embryogenesis. It is also responsible for the expression of CD15 in mature granulocytes. A common haplotype of this gene has also been associated with susceptibility to placental malaria infection. [provided by RefSeq, Nov 2011]
OrthologsView orthologs and multiple alignments for FUT9

Proteins

alpha-(1,3)-fucosyltransferase 9
Refseq ID:NP_006572
Protein GI:139394626
UniProt ID:Q9Y231
mRNA ID:NM_006581
Length:359
RefSeq Status:REVIEWED
MTSTSKGILRPFLIVCIILGCFMACLLIYIKPTNSWIFSPMESASSVLKMKNFFSTKTDYFNETTILVWVWPFGQTFDLTSCQAMFNIQGCHLTTDRSLY
NKSHAVLIHHRDISWDLTNLPQQARPPFQKWIWMNLESPTHTPQKSGIEHLFNLTLTYRRDSDIQVPYGFLTVSTNPFVFEVPSKEKLVCWVVSNWNPEH
ARVKYYNELSKSIEIHTYGQAFGEYVNDKNLIPTISTCKFYLSFENSIHKDYITEKLYNAFLAGSVPVVLGPSRENYENYIPADSFIHVEDYNSPSELAK
YLKEVDKNNKLYLSYFNWRKDFTVNLPRFWESHACLACDHVKRHQEYKSVGNLEKWFWN