LMPD Database

LMP004919

Record overview

LMPD IDLMP004919
Gene ID338596
SpeciesHomo sapiens (Human)
Gene NameST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
Gene SymbolST8SIA6
SynonymsSIA8F; SIAT8F; ST8SIA-VI
Alternate namesalpha-2,8-sialyltransferase 8F; SIAT8-F; ST8SiaVI; sialytransferase St8Sia VI; sialyltransferase St8Sia VI; alpha-2,8-sialyltransferase 8F variant 2; alpha-2,8-sialyltransferase 8F variant 3; sialyltransferase 8F (alpha-2, 8-sialyltransferase)
Chromosome10
Map Location10p12.33
EC Number2.4.99.-
SummarySialic acid is a key determinate of oligosaccharide structures involved in cell-cell communication, cell-substrate interaction, adhesion, and protein targeting. ST8SIA6 belongs to a family of sialyltransferases (EC 2.4.99.8) that synthesize sialylglycoconjugates (Takashima et al., 2002 [PubMed 11980897]).[supplied by OMIM, Mar 2008]
OrthologsView orthologs and multiple alignments for ST8SIA6

Proteins

alpha-2,8-sialyltransferase 8F precursor
Refseq ID:NP_001004470
Protein GI:54234057
UniProt ID:P61647
mRNA ID:NM_001004470
Length:398
RefSeq Status:VALIDATED
MRPGGALLALLASLLLLLLLRLLWCPADAPGRARILVEESREATHGTPAALRTLRSPATAVPRATNSTYLNEKSLQLTEKCKNLQYGIESFSNKTKGYSE
NDYLQIITDIQSCPWKRQAEEYANFRAKLASCCDAVQNFVVSQNNTPVGTNMSYEVESKKEIPIKKNIFHMFPVSQPFVDYPYNQCAVVGNGGILNKSLC
GTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKYGNLKEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEESKARQKVLFFH
PKYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTVEDIPVSHHYYDNKLPKHGFHQMPKEYSQILQLHMKGILKLQFSKCEVA
 
sig_peptide: 1..29
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3088
peptide sequence: 
MRPGGALLALLASLLLLLLLRLLWCPADA