LMPD Database

LMP004884

Record overview

LMPD IDLMP004884
Gene ID5876
SpeciesHomo sapiens (Human)
Gene NameRab geranylgeranyltransferase, beta subunit
Gene SymbolRABGGTB
SynonymsGGTB
Chromosome1
Map Location1p31
SummaryThis gene encodes the beta-subunit of the enzyme Rab geranylgeranyl-transferase (RabGGTase), which belongs to the protein prenyltransferase family. RabGGTase catalyzes the post-translational addition of geranylgeranyl groups to C-terminal cysteine residues of Rab GTPases. Three small nucleolar RNA genes are present in the intronic regions of this gene. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 3. [provided by RefSeq, Jan 2013]
OrthologsView orthologs and multiple alignments for RABGGTB

Proteins

geranylgeranyl transferase type-2 subunit beta
Refseq ID:NP_004573
Protein GI:21359854
UniProt ID:Q6IB63
mRNA ID:NM_004582
Length:331
RefSeq Status:REVIEWED
MGTPQKDVIIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLMGQLHRMNREEILAFIKSCQHECGGISASIGHDPHLLYTLS
AVQILTLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGF
LAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSL
LGEEQIKPVNPVFCMPEEVLQRVNVQPELVS