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LMP004794

Record overview

LMPD IDLMP004794
Gene ID257202
SpeciesHomo sapiens (Human)
Gene Nameglutathione peroxidase 6 (olfactory)
Gene SymbolGPX6
SynonymsGPX5p; GPXP3; GPx-6; GSHPx-6; dJ1186N24; dJ1186N24.1
Alternate namesglutathione peroxidase 6; glutathione peroxidase pseudogene 3
Chromosome6
Map Location6p22.1
EC Number1.11.1.9
SummaryThis gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Expression of this gene is restricted to embryos and adult olfactory epithelium. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for GPX6

Proteins

glutathione peroxidase 6 precursor
Refseq ID:NP_874360
Protein GI:33186887
UniProt ID:P59796
mRNA ID:NM_182701
Length:221
RefSeq Status:REVIEWED
MFQQFQASCLVLFFLVGFAQQTLKPQNRKVDCNKGVTGTIYEYGALTLNGEEYIQFKQFAGKHVLFVNVAAYUGLAAQYPELNALQEELKNFGVIVLAFP
CNQFGKQEPGTNSEILLGLKYVCPGSGFVPSFQLFEKGDVNGEKEQKVFTFLKNSCPPTSDLLGSSSQLFWEPMKVHDIRWNFEKFLVGPDGVPVMHWFH
QAPVSTVKSDILEYLKQFNTH
 
sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2197
peptide sequence: 
MFQQFQASCLVLFFLVGFA