LMPD Database

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LMP003630

Record overview

LMPD IDLMP003630
Gene ID10011
SpeciesHomo sapiens (Human)
Gene Namesteroid receptor RNA activator 1
Gene SymbolSRA1
SynonymsSRA; SRAP; STRAA1; pp7684
Chromosome5
Map Location5q31.3
SummaryBoth long non-coding and protein-coding RNAs are transcribed from this gene, and they represent alternatively spliced transcript variants. This gene was initially defined as a non-coding RNA, which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that this gene is involved in the regulation of many NR and non-NR activities, including metabolism, adipogenesis and chromatin organization. The long non-coding RNA transcripts interact with a variety of proteins, including the protein encoded by this gene. The encoded protein acts as a transcriptional repressor by binding to the non-coding RNA. [provided by RefSeq, Mar 2012]
OrthologsView orthologs and multiple alignments for SRA1

Proteins

steroid receptor RNA activator 1 isoform 1
Refseq ID:NP_001030312
Protein GI:113951734
UniProt ID:Q9HD15
mRNA ID:NM_001035235
Length:236
RefSeq Status:REVIEWED
MTRCPAGQAEVEMAELYVKPGNKERGWNDPPQFSYGLQTQAGGPRRSLLTKRVAAPQDGSPRVPASETSPGPPPMGPPPPSSKAPRSPPVGSGPASGVEP
TSFPVESEAVMEDVLRPLEQALEDCRGHTRKQVCDDISRRLALLQEQWAGGKLSIPVKKRMALLVQELSSHRWDAADDIHRSLMVDHVTEVSQWMVGVKR
LIAEKRSLFSEEAANEEKSAATAEKNHTIPGFQQAS
 
steroid receptor RNA activator 1 isoform 2
Refseq ID:NP_001240693
Protein GI:113951734
UniProt ID:Q9HD15
mRNA ID:NM_001253764
Length:236
RefSeq Status:REVIEWED
MTRCPAGQAEVEMAELYVKPGNKERGWNDPPQFSYGLQTQAGGPRRSLLTKRVAAPQDGSPRVPASETSPGPPPMGPPPPSSKAPRSPPVGSGPASGVEP
TSFPVESEAVMEDVLRPLEQALEDCRGHTRKQVCDDISRRLALLQEQWAGGKLSIPVKKRMALLVQELSSHRWDAADDIHRSLMVDHVTEVSQWMVGVKR
LIAEKRSLFSEEAANEEKSAATAEKNHTIPGFQQAS