LMPD Database

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LMP003387

Record overview

LMPD IDLMP003387
Gene ID27163
SpeciesHomo sapiens (Human)
Gene NameN-acylethanolamine acid amidase
Gene SymbolNAAA
SynonymsASAHL; PLT
Alternate namesN-acylethanolamine-hydrolyzing acid amidase; ASAH-like protein; acid ceramidase-like protein
Chromosome4
Map Location4q21.1
EC Number3.5.1.-
SummaryThis gene encodes an N-acylethanolamine-hydrolyzing enzyme which is highly similar to acid ceramidase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for NAAA

Proteins

N-acylethanolamine-hydrolyzing acid amidase isoform 1 precursor
Refseq ID:NP_055250
Protein GI:109148550
UniProt ID:Q02083
mRNA ID:NM_014435
Length:359
RefSeq Status:REVIEWED
MRTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLVRAAMAQVIGDRVPKWVHVLIGKVVLELERFLPQPFTGEIR
GMCDFMNLSLADCLLVNLAYESSVFCTSIVAQDSRGHIYHGRNLDYPFGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGLWTGQSPHKFTVSGDERDKGW
WWENAIAALFRRHIPVSWLIRATLSESENFEAAVGKLAKTPLIADVYYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDR
RTSAIKALNATGQANLSLEALFQILSVVPVYNNFTIYTTVMSAGSPDKYMTRIRNPSRK
 
sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2834
peptide sequence: 
MRTADREARPGLPSLLLLLLAGAGLSAA

mat_peptide: 29..323
product: N-acylethanolamine-hydrolyzing acid amidase isoform 2
calculated_mol_wt: 33147
peptide sequence: 
SPPAAPRFNVSLDSVPELRWLPVLRHYDLDLVRAAMAQVIGDRVPKWVHVLIGKVVLELERFLPQPFTGEIRGMCDFMNLSLADCLLVNLAYESSVFCTS
IVAQDSRGHIYHGRNLDYPFGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGLWTGQSPHKFTVSGDERDKGWWWENAIAALFRRHIPVSWLIRATLSESE
NFEAAVGKLAKTPLIADVYYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDRRTSAIKALNATGQANLSLEALFQ

sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2834
peptide sequence: 
MRTADREARPGLPSLLLLLLAGAGLSAA

mat_peptide: 29..359
product: N-acylethanolamine-hydrolyzing acid amidase isoform 1
calculated_mol_wt: 37250
peptide sequence: 
SPPAAPRFNVSLDSVPELRWLPVLRHYDLDLVRAAMAQVIGDRVPKWVHVLIGKVVLELERFLPQPFTGEIRGMCDFMNLSLADCLLVNLAYESSVFCTS
IVAQDSRGHIYHGRNLDYPFGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGLWTGQSPHKFTVSGDERDKGWWWENAIAALFRRHIPVSWLIRATLSESE
NFEAAVGKLAKTPLIADVYYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDRRTSAIKALNATGQANLSLEALFQILSVV
PVYNNFTIYTTVMSAGSPDKYMTRIRNPSRK
 
N-acylethanolamine-hydrolyzing acid amidase isoform 2 precursor
Refseq ID:NP_001035861
Protein GI:109148548
UniProt ID:Q02083
mRNA ID:NM_001042402
Length:323
RefSeq Status:REVIEWED
MRTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLVRAAMAQVIGDRVPKWVHVLIGKVVLELERFLPQPFTGEIR
GMCDFMNLSLADCLLVNLAYESSVFCTSIVAQDSRGHIYHGRNLDYPFGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGLWTGQSPHKFTVSGDERDKGW
WWENAIAALFRRHIPVSWLIRATLSESENFEAAVGKLAKTPLIADVYYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDR
RTSAIKALNATGQANLSLEALFQ