LMPD Database

LMP003386

Record overview

LMPD ID	LMP003386
Gene ID	55711
Species	Homo sapiens (Human)
Gene Name	fatty acyl CoA reductase 2
Gene Symbol	FAR2
Synonyms	MLSTD1; SDR10E2
Chromosome	12
Map Location	12p11.22
Summary	This gene belongs to the short chain dehydrogenase/reductase superfamily. It encodes a reductase enzyme involved in the first step of wax biosynthesis wherein fatty acids are converted to fatty alcohols. The encoded peroxisomal protein utilizes saturated fatty acids of 16 or 18 carbons as preferred substrates. Alternatively spliced transcript variants have been observed for this gene. Related pseudogenes have been identified on chromosomes 2, 14 and 22. [provided by RefSeq, Nov 2012]
Orthologs	View orthologs and multiple alignments for FAR2

Proteins

fatty acyl-CoA reductase 2 isoform 1

Refseq ID:	NP_060569
Protein GI:	31542658
UniProt ID:	Q9NUX8
mRNA ID:	NM_018099
Length:	515
RefSeq Status:	REVIEWED

MSTIAAFYGGKSILITGATGFLGKVLMEKLFRTSPDLKVIYILVRPKAGQTLQQRVFQILDSKLFEKVKEVCPNVHEKIRAIYADLNQNDFAISKEDMQE
LLSCTNIIFHCAATVRFDDTLRHAVQLNVTATRQLLLMASQMPKLEAFIHISTAYSNCNLKHIDEVIYPCPVEPKKIIDSLEWLDDAIIDEITPKLIRDW
PNIYTYTKALGEMVVQQESRNLNIAIIRPSIVGATWQEPFPGWVDNINGPNGIIIATGKGFLRAIKATPMAVADVIPVDTVVNLMLAVGWYTAVHRPKST
LVYHITSGNMNPCNWHKMGVQVLATFEKIPFERPFRRPNANFTSNSFTSQYWNAVSHRAPAIIYDCYLRLTGRKPRMTKLMNRLLRTVSMLEYFINRSWE
WSTYNTEMLMSELSPEDQRVFNFDVRQLNWLEYIENYVLGVKKYLLKEDMAGIPKAKQRLKRLRNIHYLFNTALFLIAWRLLIARSQMARNVWFFIVSFC
YKFLSYFRASSTLKV

fatty acyl-CoA reductase 2 isoform 1

Refseq ID:	NP_001258712
Protein GI:	422398861
UniProt ID:	Q9NUX8
mRNA ID:	NM_001271783
Length:	515
RefSeq Status:	REVIEWED

fatty acyl-CoA reductase 2 isoform 2
Protein sequence is identical to GI:31542658 (mRNA isoform)

Refseq ID:	NP_001258713
Protein GI:	422398861
UniProt ID:	Q9NUX8
mRNA ID:	NM_001271784
Length:	515
RefSeq Status:	REVIEWED

Protein sequence is identical to GI:31542658 (mRNA isoform)