LMPD Database

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LMP003177

Record overview

LMPD IDLMP003177
Gene ID29956
SpeciesHomo sapiens (Human)
Gene Nameceramide synthase 2
Gene SymbolCERS2
SynonymsL3; LASS2; SP260; TMSG1
Alternate namesceramide synthase 2; LAG1 longevity assurance 2; LAG1 homolog, ceramide synthase 2; tumor metastasis-suppressor gene 1 protein; longevity assurance (LAG1, S. cerevisiae) homolog 2
Chromosome1
Map Location1q21.3
SummaryThis gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for CERS2

Proteins

ceramide synthase 2
Refseq ID:NP_071358
Protein GI:31077094
UniProt ID:Q96G23
mRNA ID:NM_022075
Length:380
RefSeq Status:REVIEWED
MLQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYVATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEV
ELLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQYWYYMIELSFYWSLLFSIASD
VKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHDSSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFF
GYYFFNSMMGVLQLLHIFWAYLILRMAHKFITGKLVEDERSDREETESSEGEEAAAGGGAKSRPLANGHPILNNNHRKND
 
ceramide synthase 2
Refseq ID:NP_859530
Protein GI:32455256
UniProt ID:Q96G23
mRNA ID:NM_181746
Length:380
RefSeq Status:REVIEWED
Protein sequence is identical to GI:31077094 (mRNA isoform)