LMPD Database

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LMP002444

UniProt Annotations

Entry Information
Gene Namedolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
Protein EntryGPT_HUMAN
UniProt IDQ9H3H5
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q9H3H5-1; Sequence=Displayed; Name=2; IsoId=Q9H3H5-2; Sequence=VSP_001803; Note=No experimental confirmation available.; Name=3; IsoId=Q9H3H5-3; Sequence=VSP_008886; Note=No experimental confirmation available.;
Catalytic ActivityUDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol.
DiseaseCongenital disorder of glycosylation 1J (CDG1J) [MIM
DiseaseMyasthenic syndrome, congenital, with tubular aggregates, 2 (CMSTA2) [MIM
FunctionCatalyzes the initial step in the synthesis of dolichol- P-P-oligosaccharides.
PathwayProtein modification; protein glycosylation.
SimilarityBelongs to the glycosyltransferase 4 family.
Subcellular LocationEndoplasmic reticulum membrane; Multi-pass membrane protein.
Web ResourceName=Functional Glycomics Gateway - GTase; Note=UDP- N-acetylglucosamine--dolichyl-phosphate N- acetylglucosaminephosphotransferase; URL="http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_543";
Web ResourceName=GGDB; Note=GlycoGene database; URL="http://jcggdb.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=DPAGT1";