LMPD Database

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LMP002315

Record overview

LMPD IDLMP002315
Gene ID10998
SpeciesHomo sapiens (Human)
Gene Namesolute carrier family 27 (fatty acid transporter), member 5
Gene SymbolSLC27A5
SynonymsACSB; ACSVL6; BACS; BAL; FACVL3; FATP-5; FATP5; VLACSR; VLCS-H2; VLCSH2
Alternate namesbile acyl-CoA synthetase; BA-CoA ligase; VLACS-related; cholate--CoA ligase; bile acid-CoA ligase; fatty acid transport protein 5; solute carrier family 27 member 5; very long-chain acyl-CoA synthetase homolog 2; fatty-acid-Coenzyme A ligase, very long-chain 3; very long-chain acyl-CoA synthetase-related protein
Chromosome19
Map Location19q13.43
EC Number6.2.1.7
SummaryThe protein encoded by this gene is an isozyme of very long-chain acyl-CoA synthetase (VLCS). It is capable of activating very long-chain fatty-acids containing 24- and 26-carbons. It is expressed in liver and associated with endoplasmic reticulum but not with peroxisomes. Its primary role is in fatty acid elongation or complex lipid synthesis rather than in degradation. This gene has a mouse ortholog. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for SLC27A5

Proteins

bile acyl-CoA synthetase precursor
Refseq ID:NP_036386
Protein GI:13325057
UniProt ID:Q9Y2P5
mRNA ID:NM_012254
Length:690
RefSeq Status:REVIEWED
MGVRQQLALLLLLLLLLWGLGQPVWPVAVALTLRWLLGDPTCCVLLGLAMLARPWLGPWVPHGLSLAAAALALTLLPARLPPGLRWLPADVIFLAKILHL
GLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELDARACQAAWALKAELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCP
TAWINPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPTPGVGALGAALDAAPSHPVPADLRAGITWRSPALFIYTSGTTG
LPKPAILTHERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRT
HTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVV
SQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQ
LAPGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQAVCEGTWRL
 
sig_peptide: 1..21
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2334
peptide sequence: 
MGVRQQLALLLLLLLLLWGLG