LMPD Database

LMP001974

Record overview

LMPD ID	LMP001974
Gene ID	35
Species	Homo sapiens (Human)
Gene Name	acyl-CoA dehydrogenase, C-2 to C-3 short chain
Gene Symbol	ACADS
Synonyms	ACAD3; SCAD
Chromosome	12
Map Location	12q24.31
Summary	This gene encodes a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with short-chain acyl-CoA dehydrogenase (SCAD) deficiency. Alternative splicing results in two variants which encode different isoforms. [provided by RefSeq, Oct 2014]
Orthologs	View orthologs and multiple alignments for ACADS

Proteins

short-chain specific acyl-CoA dehydrogenase, mitochondrial isoform 1 precursor

Refseq ID:	NP_000008
Protein GI:	4557233
UniProt ID:	P16219
mRNA ID:	NM_000017
Length:	412
RefSeq Status:	REVIEWED

MAAALLARASGPARRALCPRAWRQLHTIYQSVELPETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGAGLDYLAYAI
AMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFAS
TDRALQNKGISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQTLDMGRIGIASQALGIAQTALDCAVNYAENRMAF
GAPLTKLQVIQFKLADMALALESARLLTWRAAMLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSEIQRL
VIAGHLLRSYRS

short-chain specific acyl-CoA dehydrogenase, mitochondrial isoform 2 precursor

Refseq ID:	NP_001289483
Protein GI:	4557233
UniProt ID:	P16219
mRNA ID:	NM_001302554
Length:	412
RefSeq Status:	REVIEWED

MAAALLARASGPARRALCPRAWRQLHTIYQSVELPETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGAGLDYLAYAI
AMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFAS
TDRALQNKGISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQTLDMGRIGIASQALGIAQTALDCAVNYAENRMAF
GAPLTKLQVIQFKLADMALALESARLLTWRAAMLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSEIQRL
VIAGHLLRSYRS