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LMP001971

Record overview

LMPD IDLMP001971
Gene ID10331
SpeciesHomo sapiens (Human)
Gene NameUDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
Gene SymbolB3GNT3
SynonymsB3GAL-T8; B3GN-T3; B3GNT-3; HP10328; TMEM3; beta3Gn-T3
Alternate namesUDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3; beta3GalT8; beta-3-Gx-T8; beta-1,3-Gn-T3; beta-1,3-GalTase 8; core1-beta3GlcNAcT; transmembrane protein 3; putative type II membrane protein; beta-1,3-N-acetylglucosaminyltransferase bGnT-3; UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 8; core 1 extending beta-1,3-N-acetylglucosaminyltransferase; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 8
Chromosome19
Map Location19p13.1
EC Number2.4.1.146
SummaryThis gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for B3GNT3

Proteins

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
Refseq ID:NP_055071
Protein GI:92091604
UniProt ID:Q9Y2A9
mRNA ID:NM_014256
Length:372
RefSeq Status:REVIEWED
MKYLRHRRPNATLILAIGAFTLLLFSLLVSPPTCKVQEQPPAIPEALAWPTPPTRPAPAPCHANTSMVTHPDFATQPQHVQNFLLYRHCRHFPLLQDVPP
SKCAQPVFLLLVIKSSPSNYVRRELLRRTWGRERKVRGLQLRLLFLVGTASNPHEARKVNRLLELEAQTHGDILQWDFHDSFFNLTLKQVLFLQWQETRC
ANASFVLNGDDDVFAHTDNMVFYLQDHDPGRHLFVGQLIQNVGPIRAFWSKYYVPEVVTQNERYPPYCGGGGFLLSRFTAAALRRAAHVLDIFPIDDVFL
GMCLELEGLKPASHSGIRTSGVRAPSQRLSSFDPCFYRDLLLVHRFLPYEMLLMWDALNQPNLTCGNQTQIY