LMPD Database

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LMP001838

Record overview

LMPD IDLMP001838
Gene ID200879
SpeciesHomo sapiens (Human)
Gene Namelipase, member H
Gene SymbolLIPH
SynonymsAH; ARWH2; HYPT7; LAH2; LPDLR; PLA1B; mPA-PLA1
Alternate nameslipase member H; lipase H; mPA-PLA1 alpha; phospholipase A1 member B; LPD lipase-related protein; membrane-bound phosphatidic acid-selective phospholipase A1; membrane-associated phosphatidic acid-selective phospholipase A1-alpha
Chromosome3
Map Location3q27
EC Number3.1.1.-
SummaryThis gene encodes a membrane-bound member of the mammalian triglyceride lipase family. It catalyzes the production of 2-acyl lysophosphatidic acid (LPA), which is a lipid mediator with diverse biological properties that include platelet aggregation, smooth muscle contraction, and stimulation of cell proliferation and motility. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for LIPH

Proteins

lipase member H precursor
Refseq ID:NP_640341
Protein GI:21245106
UniProt ID:Q8WWY8
mRNA ID:NM_139248
Length:451
RefSeq Status:REVIEWED
MLRFYLFISLLCLSRSDAEETCPSFTRLSFHSAVVGTGLNVRLMLYTRKNLTCAQTINSSAFGNLNVTKKTTFIVHGFRPTGSPPVWMDDLVKGLLSVED
MNVVVVDWNRGATTLIYTHASSKTRKVAMVLKEFIDQMLAEGASLDDIYMIGVSLGAHISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQDRLDPSDAQF
VDVIHSDTDALGYKEPLGNIDFYPNGGLDQPGCPKTILGGFQYFKCDHQRSVYLYLSSLRESCTITAYPCDSYQDYRNGKCVSCGTSQKESCPLLGYYAD
NWKDHLRGKDPPMTKAFFDTAEESPFCMYHYFVDIITWNKNVRRGDITIKLRDKAGNTTESKINHEPTTFQKYHQVSLLARFNQDLDKVAAISLMFSTGS
LIGPRYKLRILRMKLRSLAHPERPQLCRYDLVLMENVETVFQPILCPELQL
 
sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2149
peptide sequence: 
MLRFYLFISLLCLSRSDA

mat_peptide: 19..451
product: lipase member H
calculated_mol_wt: 48729
peptide sequence: 
EETCPSFTRLSFHSAVVGTGLNVRLMLYTRKNLTCAQTINSSAFGNLNVTKKTTFIVHGFRPTGSPPVWMDDLVKGLLSVEDMNVVVVDWNRGATTLIYT
HASSKTRKVAMVLKEFIDQMLAEGASLDDIYMIGVSLGAHISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSDTDALGYKEPLG
NIDFYPNGGLDQPGCPKTILGGFQYFKCDHQRSVYLYLSSLRESCTITAYPCDSYQDYRNGKCVSCGTSQKESCPLLGYYADNWKDHLRGKDPPMTKAFF
DTAEESPFCMYHYFVDIITWNKNVRRGDITIKLRDKAGNTTESKINHEPTTFQKYHQVSLLARFNQDLDKVAAISLMFSTGSLIGPRYKLRILRMKLRSL
AHPERPQLCRYDLVLMENVETVFQPILCPELQL