LMPD Database

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LMP001666

UniProt Annotations

Entry Information
Gene NameUDP-glucose ceramide glucosyltransferase
Protein EntryCEGT_HUMAN
UniProt IDQ16739
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityUDP-glucose + N-acylsphingosine = UDP + D- glucosyl-N-acylsphingosine.
FunctionCatalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase".
PathwayLipid metabolism; sphingolipid metabolism.
SimilarityBelongs to the glycosyltransferase 2 family.
Subcellular LocationGolgi apparatus membrane ; Multi-pass membrane protein .
Tissue SpecificityFound in all tissues examined.
Web ResourceName=GGDB; Note=GlycoGene database; URL="http://jcggdb.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=UGCG";