LMPD Database

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LMP001605

Record overview

LMPD IDLMP001605
Gene ID9023
SpeciesHomo sapiens (Human)
Gene Namecholesterol 25-hydroxylase
Gene SymbolCH25H
SynonymsC25H
Alternate namescholesterol 25-hydroxylase; h25OH; cholesterol 25-monooxygenase
Chromosome10
Map Location10q23
EC Number1.14.99.38
SummaryThis is an intronless gene that is involved in cholesterol and lipid metabolism. The encoded protein is a membrane protein and contains clusters of histidine residues essential for catalytic activity. Unlike most other sterol hydroxylases, this enzyme is a member of a small family of enzymes that utilize diiron cofactors to catalyze the hydroxylation of hydrophobic substrates. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for CH25H

Proteins

cholesterol 25-hydroxylase
Refseq ID:NP_003947
Protein GI:4502499
UniProt ID:O95992
mRNA ID:NM_003956
Length:272
RefSeq Status:REVIEWED
MSCHNCSDPQVLCSSGQLFLQPLWDHLRSWEALLQSPFFPVIFSITTYVGFCLPFVVLDILCSWVPALRRYKIHPDFSPSAQQLLPCLGQTLYQHVMFVF
PVTLLHWARSPALLPHEAPELLLLLHHILFCLLLFDMEFFVWHLLHHKVPWLYRTFHKVHHQNSSSFALATQYMSVWELFSLGFFDMMNVTLLGCHPLTT
LTFHVVNIWLSVEDHSGYNFPWSTHRLVPFGWYGGVVHHDLHHSHFNCNFAPYFTHWDKILGTLRTASVPAR