LMPD Database

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LMP001565

Record overview

LMPD IDLMP001565
Gene ID20598
SpeciesMus musculus(Mouse)
Gene Namesphingomyelin phosphodiesterase 2, neutral
Gene SymbolSmpd2
SynonymsAW108287; nSMase; nSMase1
Alternate namessphingomyelin phosphodiesterase 2; N-SMase; lyso-PAF-PLC; neutral sphingomyelinase 1; lyso-platelet-activating factor-phospholipase C
Chromosome10
Map Location10 B2|10
EC Number3.1.4.12
SummaryThis gene encodes a protein with similarity to the human nSMase1 protein. In humans, the nSMase1 protein was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase. [provided by RefSeq, Oct 2009]
OrthologsView orthologs and multiple alignments for Smpd2

Proteins

sphingomyelin phosphodiesterase 2
Refseq ID:NP_033239
Protein GI:6678031
UniProt ID:O70572
mRNA ID:NM_009213
Length:419
RefSeq Status:VALIDATED
MKLNFSLRLRVFNLNCWDIPYLSKHRADRMKRLGDFLNLENFDLALLEEVWSEQDFQYLRQRLSLTYPDAHYFRSGMIGSGLCVFSKHPIQEIFQHVYSL
NGYPYMFHHGDWFCGKSVGLLVLRLSGLVLNAYVTHLHAEYSRQKDIYFAHRVAQAWELAQFIHHTSKNADVVLLCGDLNMHPKDLGCCLLKEWTGLHDA
FVETEDFKGSDDGCTMVPKNCYVSQQDLGPFPSGIRIDYVLYKAVSEFHVCCETLKTTTGCDPHSDKPFSDHEALMATLYVKHSPPQEDPCTACGPLERS
DLISVLREARTELGLGIAKARWWAAFSGYVIVWGLSLLVLLCVLAAGEEAREVAIILCIPSVGLVLVAGAVYLFHKQEAKGLCRAQAEMLHVLTRETETQ
DRGSEPHLAYCLQQEGDRA