LMPD Database

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LMP001552

Record overview

LMPD IDLMP001552
Gene ID8698
SpeciesHomo sapiens (Human)
Gene Namesphingosine-1-phosphate receptor 4
Gene SymbolS1PR4
SynonymsEDG6; LPC1; S1P4; SLP4
Alternate namessphingosine 1-phosphate receptor 4; S1P receptor 4; S1P receptor Edg-6; sphingosine 1-phosphate receptor Edg-6; endothelial differentiation G-protein coupled receptor 6; endothelial differentiation, G protein coupled receptor 6; endothelial differentiation, G-protein-coupled receptor 6; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6
Chromosome19
Map Location19p13.3
SummaryThis gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for S1PR4

Proteins

sphingosine 1-phosphate receptor 4 precursor
Refseq ID:NP_003766
Protein GI:4503459
UniProt ID:O95977
mRNA ID:NM_003775
Length:384
RefSeq Status:REVIEWED
MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYL
ANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLY
SKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRSI
 
sig_peptide: 1..22
calculated_mol_wt: 2127
peptide sequence: 
MNATGTPVAPESCQQLAAGGHS

mat_peptide: 23..384
product: sphingosine 1-phosphate receptor 4
calculated_mol_wt: 39514
peptide sequence: 
RLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLRE
GLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGL
YGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFL
CCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRSI