LMPD Database

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LMP001293

Record overview

LMPD IDLMP001293
Gene ID1902
SpeciesHomo sapiens (Human)
Gene Namelysophosphatidic acid receptor 1
Gene SymbolLPAR1
SynonymsEDG2; GPR26; Gpcr26; LPA1; Mrec1.3; VZG1; edg-2; rec.1.3; vzg-1
Chromosome9
Map Location9q31.3
SummaryThe integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for LPAR1

Proteins

lysophosphatidic acid receptor 1
Refseq ID:NP_001392
Protein GI:16950636
UniProt ID:Q5VZX0
mRNA ID:NM_001401
Length:364
RefSeq Status:REVIEWED
MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGL
AYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAP
LYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA
EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSNDHSVV
 
lysophosphatidic acid receptor 1
Refseq ID:NP_476500
Protein GI:16950638
UniProt ID:Q5VZX0
mRNA ID:NM_057159
Length:364
RefSeq Status:REVIEWED
Protein sequence is identical to GI:16950636 (mRNA isoform)