LMPD Database

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LMP000912

Record overview

LMPD IDLMP000912
Gene ID2169
SpeciesHomo sapiens (Human)
Gene Namefatty acid binding protein 2, intestinal
Gene SymbolFABP2
SynonymsFABPI; I-FABP
Alternate namesfatty acid-binding protein, intestinal; fatty acid-binding protein 2; intestinal-type fatty acid-binding protein
Chromosome4
Map Location4q28-q31
SummaryThe intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for FABP2

Proteins

fatty acid-binding protein, intestinal
Refseq ID:NP_000125
Protein GI:194097325
UniProt ID:P12104
mRNA ID:NM_000134
Length:132
RefSeq Status:REVIEWED
MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSTFRNIEVVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNG
NELNTVREIIGDELVQTYVYEGVEAKRIFKKD