LMPD Database

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LMP000592

Record overview

LMPD IDLMP000592
Gene ID4835
SpeciesHomo sapiens (Human)
Gene NameNAD(P)H dehydrogenase, quinone 2
Gene SymbolNQO2
SynonymsDHQV; DIA6; NMOR2; QR2
Chromosome6
Map Location6p25.2
SummaryThis gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
OrthologsView orthologs and multiple alignments for NQO2

Proteins

ribosyldihydronicotinamide dehydrogenase [quinone] isoform 1
Refseq ID:NP_000895
Protein GI:156564357
UniProt ID:P16083
mRNA ID:NM_000904
Length:231
RefSeq Status:REVIEWED
MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIF
QFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEE
RKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ
 
ribosyldihydronicotinamide dehydrogenase [quinone] isoform 1
Refseq ID:NP_001277150
Protein GI:589811530
UniProt ID:P16083
mRNA ID:NM_001290221
Length:231
RefSeq Status:REVIEWED
Protein sequence is identical to GI:156564357 (mRNA isoform)
 
ribosyldihydronicotinamide dehydrogenase [quinone] isoform 2
Refseq ID:NP_001277151
Protein GI:589811532
UniProt ID:Q5TD07
mRNA ID:NM_001290222
Length:193
RefSeq Status:REVIEWED
MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIF
QGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ