LMPD Database

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LMP000539

Record overview

LMPD IDLMP000539
Gene ID8611
SpeciesHomo sapiens (Human)
Gene Namephosphatidic acid phosphatase type 2A
Gene SymbolPPAP2A
SynonymsLLP1a; LPP1; PAP-2a; PAP2
Alternate nameslipid phosphate phosphohydrolase 1; phosphatidic acid phosphatase 2a; lipid phosphate phosphohydrolase 1a; phosphatidate phosphohydrolase type 2a; phosphatidic acid phosphohydrolase type 2a; type-2 phosphatidic acid phosphatase alpha
Chromosome5
Map Location5q11
EC Number3.1.3.4
SummaryThe protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in synthesis of glycerolipids and in phospholipase D-mediated signal transduction. This enzyme is an integral membrane glycoprotein that plays a role in the hydrolysis and uptake of lipids from extracellular space. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
OrthologsView orthologs and multiple alignments for PPAP2A

Proteins

lipid phosphate phosphohydrolase 1 isoform 1
Refseq ID:NP_003702
Protein GI:29171736
UniProt ID:O14494
mRNA ID:NM_003711
Length:284
RefSeq Status:REVIEWED
MFDKTRLPYVALDVLCVLLAGLPFAILTSRHTPFQRGVFCNDESIKYPYKEDTIPYALLGGIIIPFSIIVIILGETLSVYCNLLHSNSFIRNNYIATIYK
AIGTFLFGAAASQSLTDIAKYSIGRLRPHFLDVCDPDWSKINCSDGYIEYYICRGNAERVKEGRLSFYSGHSSFSMYCMLFVALYLQARMKGDWARLLRP
TLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVAILVAVYVSDFFKERTSFKERKEEDSHTTLHETPTTGNHYPSNHQP
 
lipid phosphate phosphohydrolase 1 isoform 2
Refseq ID:NP_795714
Protein GI:29171738
UniProt ID:O14494
mRNA ID:NM_176895
Length:285
RefSeq Status:REVIEWED
MFDKTRLPYVALDVLCVLLASMPMAVLKLGQIYPFQRGFFCKDNSINYPYHDSTVTSTVLILVGVGLPISSIILGETLSVYCNLLHSNSFIRNNYIATIY
KAIGTFLFGAAASQSLTDIAKYSIGRLRPHFLDVCDPDWSKINCSDGYIEYYICRGNAERVKEGRLSFYSGHSSFSMYCMLFVALYLQARMKGDWARLLR
PTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVAILVAVYVSDFFKERTSFKERKEEDSHTTLHETPTTGNHYPSNHQP