LMPD Database

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LMP000518

Record overview

LMPD IDLMP000518
Gene ID9488
SpeciesHomo sapiens (Human)
Gene Namephosphatidylinositol glycan anchor biosynthesis, class B
Gene SymbolPIGB
SynonymsGPI-MT-III; PIG-B
Alternate namesGPI mannosyltransferase 3; GPI mannosyltransferase III; phosphatidylinositol glycan, class B; dol-P-Man dependent GPI mannosyltransferase; phosphatidylinositol-glycan biosynthesis class B protein
Chromosome15
Map Location15q21.3
EC Number2.4.1.-
SummaryThis gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene is thought to encode a member of a family of dolichol-phosphate-mannose (Dol-P-Man) dependent mannosyltransferases. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for PIGB

Proteins

GPI mannosyltransferase 3
Refseq ID:NP_004846
Protein GI:110224465
UniProt ID:Q92521
mRNA ID:NM_004855
Length:554
RefSeq Status:REVIEWED
MRRPLSKCGMEPGGGDASLTLHGLQNRSHGKIKLRKRKSTLYFNTQEKSARRRGDLLGENIYLLLFTIALRILNCFLVQTSFVPDEYWQSLEVSHHMVFN
YGYLTWEWTERLRSYTYPLIFASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWVFFCQLCSWFTWYCCTRTLTNTMETVL
TIIALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWTPLLFRHFCQEPRKLDLILHHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWG
TFYGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYSLTHLKTWKKPALSFLFLSNLFLA
LYTGLVHQRGTLDVMSHIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFLQCPPDLTGKSHYLDEADVFYLNPLNWLHREFHDDASLPTHLIT
FSILEEEISAFLISSNYKRTAVFFHTHLPEGRIGSHIYVYERKLKGKFNMKMKF