LMPD Database

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LMP000500

Record overview

LMPD IDLMP000500
Gene ID5346
SpeciesHomo sapiens (Human)
Gene Nameperilipin 1
Gene SymbolPLIN1
SynonymsFPLD4; PERI; PLIN
Alternate namesperilipin-1; lipid droplet-associated protein
Chromosome15
Map Location15q26
SummaryThe protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Feb 2009]
OrthologsView orthologs and multiple alignments for PLIN1

Proteins

perilipin-1
Refseq ID:NP_002657
Protein GI:223718196
UniProt ID:O60240
mRNA ID:NM_002666
Length:522
RefSeq Status:REVIEWED
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEE
KIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLALGSIEKVVEYLLPPDKEESA
PAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTD
TEGEDTEEEEELETEENKFSEVAALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLGMAGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNVVDTVVH
YVPLPRLSLMEPESEFRDIDNPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAPRPGFPAVPREKPKRRVSDSF
FRPSVMEPILGRTHYSQLRKKS
 
perilipin-1
Refseq ID:NP_001138783
Protein GI:223718203
UniProt ID:O60240
mRNA ID:NM_001145311
Length:522
RefSeq Status:REVIEWED
Protein sequence is identical to GI:223718196 (mRNA isoform)