LMPD Database

LMP000303

Gene Information

Entrez Gene ID	3633
Gene Name	inositol polyphosphate-5-phosphatase, 75kDa
Gene Symbol	INPP5B
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IDA:HPA	C	cytoplasm
GO:0031410	IEA:UniProtKB-KW	C	cytoplasmic vesicle
GO:0005829	IDA:UniProtKB	C	cytosol
GO:0005768	IEA:UniProtKB-KW	C	endosome
GO:0005794	IEA:UniProtKB-KW	C	Golgi apparatus
GO:0016021	IEA:Ensembl	C	integral component of membrane
GO:0016020	IDA:UniProtKB	C	membrane
GO:0015630	IDA:HPA	C	microtubule cytoskeleton
GO:0005886	TAS:Reactome	C	plasma membrane
GO:0052658	IDA:UniProtKB	F	inositol-1,4,5-trisphosphate 5-phosphatase activity
GO:0046872	IEA:UniProtKB-KW	F	metal ion binding
GO:0004439	IDA:UniProtKB	F	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0043647	TAS:Reactome	P	inositol phosphate metabolic process
GO:0001701	IEA:Ensembl	P	in utero embryonic development
GO:0046856	IDA:UniProtKB	P	phosphatidylinositol dephosphorylation
GO:0070613	IEA:Ensembl	P	regulation of protein processing
GO:0051056	TAS:Reactome	P	regulation of small GTPase mediated signal transduction
GO:0007264	TAS:Reactome	P	small GTPase mediated signal transduction
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0007283	IEA:Ensembl	P	spermatogenesis
GO:0030317	IEA:Ensembl	P	sperm motility

BIOCYC Pathway Links

BIOCYC Pathway ID	Description
PWY-6362	1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)
PWY-6364	D-myo-inositol (1,3,4)-trisphosphate biosynthesis

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_150352	Synthesis of IP2, IP, and Ins in the cytosol
REACT_150312	Synthesis of IP3 and IP4 in the cytosol