LMPD Database

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LMP000249

UniProt Annotations

Entry Information
Gene Namefucosyltransferase 7 (alpha (1,3) fucosyltransferase)
Protein EntryFUT7_HUMAN
UniProt IDQ11130
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityGDP-L-fucose + alpha-2,3-Neu-N-acetyl-1,4- beta-D-galactosyl-N-acetyl-D-glucosaminyl-R = GDP + alpha-2,3-Neu- N-acetyl-1,4-beta-D-galactosyl-(alpha-1,3-L-fucosyl)-N-acetyl-D- glucosaminyl-R.
FunctionMay catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens.
PathwayProtein modification; protein glycosylation.
SimilarityBelongs to the glycosyltransferase 10 family.
Subcellular LocationGolgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Tissue SpecificityLeukocytic/myeloid lineage cells.
Web ResourceName=Functional Glycomics Gateway - GTase; Note=Fucosyltransferase 7; URL="http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_604";
Web ResourceName=GGDB; Note=GlycoGene database; URL="http://jcggdb.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=FUT7";