LMPD Database

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LMP000231

Record overview

LMPD IDLMP000231
Gene ID80339
SpeciesHomo sapiens (Human)
Gene Namepatatin-like phospholipase domain containing 3
Gene SymbolPNPLA3
SynonymsADPN; C22orf20; iPLA(2)epsilon
Alternate namespatatin-like phospholipase domain-containing protein 3; adiponutrin; iPLA2epsilon; iPLA2-epsilon; acylglycerol O-acyltransferase; calcium-independent phospholipase A2-epsilon
Chromosome22
Map Location22q13.31
EC Number3.1.1.3
SummaryThe protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for PNPLA3

Proteins

patatin-like phospholipase domain-containing protein 3
Refseq ID:NP_079501
Protein GI:17196626
UniProt ID:Q9NST1
mRNA ID:NM_025225
Length:481
RefSeq Status:REVIEWED
MYDAERGWSLSFAGCGFLGFYHVGATRCLSEHAPHLLRDARMLFGASAGALHCVGVLSGIPLEQTLQVLSDLVRKARSRNIGIFHPSFNLSKFLRQGLCK
CLPANVHQLISGKIGISLTRVSDGENVLVSDFRSKDEVVDALVCSCFIPFYSGLIPPSFRGVRYVDGGVSDNVPFIDAKTTITVSPFYGEYDICPKVKST
NFLHVDITKLSLRLCTGNLYLLSRAFVPPDLKVLGEICLRGYLDAFRFLEEKGICNRPQPGLKSSSEGMDPEVAMPSWANMSLDSSPESAALAVRLEGDE
LLDHLRLSILPWDESILDTLSPRLATALSEEMKDKGGYMSKICNLLPIRIMSYVMLPCTLPVESAIAIVQRLVTWLPDMPDDVLWLQWVTSQVFTRVLMC
LLPASRSQMPVSSQQASPCTPEQDWPCWTPCSPKGCPAETKAEATPRSILRSSLNFFLGNKVPAGAEGLSTFPSFSLEKSL