Research library - Protein Structure and Function

This library is a growing collection of the most significant research advances and key review articles, categorized by subject areas, from across the literature.

2012

  • Antidiabetic phospholipid–nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation

    Musille P., Pathak M., Lauer J., Hudson W., Griffin P. et al.

    Nat Struct Mol Biol (Published online 15 April 2012)

    [doi: 10.1038/nsmb.2279]

  • Essential Role of ELOVL4 Protein in Very Long Chain Fatty Acid Synthesis and Retinal Function

    Harkewicz R., Du H., Tong Z., Alkuraya H., Bedell M. et al.

    Journal of Biological Chemistry 287, (2012)

    [doi: 10.1074/jbc.M111.256073]

  • Pho85p-Pho80p Phosphorylation of Yeast Pah1p Phosphatidate Phosphatase Regulates Its Activity, Location, Abundance, and Function in Lipid Metabolism

    Choi H., Su W., Han G., Plote D., Xu Z. et al.

    Journal of Biological Chemistry 287, (2012)

    [doi: 10.1074/jbc.M112.346023]

  • Genome-wide Functional Annotation of Dual-Specificity Protein- and Lipid-Binding Modules that Regulate Protein Interactions

    Chen Y., Sheng R., K�llberg M., Silkov A., Tun M. et al.

    Molecular Cell (Published online 1 March 2012)

    [doi: 10.1016/j.molcel.2012.02.012]

  • Affinity of talin-1 for the β3-integrin cytosolic domain is modulated by its phospholipid bilayer environment

    Moore D., Nygren P., Jo H., Boesze-Battaglia K., Bennett J. et al.

    Proceedings of the National Academy of Sciences 109, (2012)

    [doi: 10.1073/pnas.1117220108]

  • A catalytically silent FAAH-1 variant drives anandamide transport in neurons

    Fu J., Bottegoni G., Sasso O., Bertorelli R., Rocchia W. et al.

    Nat Neurosci 15, 64 - 69 (2012)

    [doi: 10.1038/nn.2986]

  • Natural Diterpenoid Compound Elevates Expression of Bim Protein, Which Interacts with Antiapoptotic Protein Bcl-2, Converting It to Proapoptotic Bax-like Molecule

    Zhao L., He F., Liu H., Zhu Y., Tian W. et al.

    Journal of Biological Chemistry 287, (2012)

    [doi: 10.1074/jbc.M111.264481]

  • Oleosin Is Bifunctional Enzyme That Has Both Monoacylglycerol Acyltransferase and Phospholipase Activities

    Parthibane V., Rajakumari S., Venkateshwari V., Iyappan R. and Rajasekharan R.

    Journal of Biological Chemistry 287, (2012)

    [doi: 10.1074/jbc.M111.309955]

  • Structure of HDAC3 bound to co-repressor and inositol tetraphosphate

    Watson P., Fairall L., Santos G. and Schwabe J.

    Nature (Published online 9 January 2012)

    [doi: 10.1038/nature10728]

  • Molecular recognition of a single sphingolipid species by a protein's transmembrane domain

    Contreras F.-X., Ernst A., Haberkant P., Bjorkholm P., Lindahl E. et al.

    Nature (Published online 9 January 2012)

    [doi: 10.1038/nature10742]

  • Structural rearrangements underlying ligand-gating in Kir channels

    Wang S., Lee S., Heyman S., Enkvetchakul D. and Nichols C.

    Nat Commun 3, 617 (2012)

    [doi: 10.1038/ncomms1625]

  • Structure of saposin A lipoprotein discs

    Popovic K., Holyoake J., Pomes R. and Prive G.

    Proceedings of the National Academy of Sciences 109, (2012)

    [doi: 10.1073/pnas.1115743109]

  • An intrinsically labile [alpha]-helix abutting the BCL9-binding site of [beta]-catenin is required for its inhibition by carnosic acid

    de la Roche M., Rutherford T., Gupta D., Veprintsev D., Saxty B. et al.

    Nat Commun 3, 680 (2012)

    [doi: 10.1038/ncomms1680]

  • Inhibitory effect of dietary lipids on chaperone-mediated autophagy

    Rodriguez-Navarro J., Kaushik S., Koga H., Dall'Armi C., Shui G. et al.

    Proceedings of the National Academy of Sciences 109, (2012)

    [doi: 10.1073/pnas.1113036109]

  • Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers

    de Saint-Jean M., Delfosse V., Douguet D., Chicanne G., Payrastre B. et al.

    The Journal of Cell Biology 195, (2011)

    [doi: 10.1083/jcb.201104062]

  • A Glycosphingolipid/Caveolin-1 Signaling Complex Inhibits Motility of Human Ovarian Carcinoma Cells

    Prinetti A., Cao T., Illuzzi G., Prioni S., Aureli M. et al.

    Journal of Biological Chemistry 286, (2011)

    [doi: 10.1074/jbc.M111.286146]

  • Integrin adhesion and force coupling are independently regulated by localized PtdIns(4,5)2 synthesis

    Legate K., Takahashi S., Bonakdar N., Fabry B., Boettiger D. et al.

    EMBO J (Published online 16 September 2011)

    [doi: 10.1038/emboj.2011.332]

  • Crystal Structure of the Human K2P TRAAK, a Lipid- and Mechano-Sensitive K+ Ion Channel

    Brohawn S., del Marmol J. and MacKinnon R.

    Science 335, (2012)

    [doi: 10.1126/science.1213808]

  • Myosin I Links PIP3 Signaling to Remodeling of the Actin Cytoskeleton in Chemotaxis

    Chen C., Wang Y., Sesaki H. and Iijima M.

    Science Signaling 5, (2012)

    [doi: 10.1126/scisignal.2002446]

  • Regulation of inositol 1,3,4 -trisphosphate 5/6-kinase (ITPK1) by reversible lysine acetylation

    Zhang C., Majerus P. and Wilson M.

    Proceedings of the National Academy of Sciences (Published online 14 February 2012)

    [doi: 10.1073/pnas.1119740109]

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