Lipidomics update - April, 2018
The lipidomics update provides an overview of developments in lipid research. Each month we offer a fresh collection of research, news and events for the specialist and the interested non-specialist alike.
LIPID MAPS® highlights
MS Analysis Tools - Perform searches with precursor ion or product ion peaklists on a variety of lipid classes, where structures are generated by computational methods or are present in the LIPID MAPS structure database. Display various structural properties (exact mass, formula, abbreviation, etc.) for matched ions with links to molecular structures and isotopic distribution profiles where appropriate. Generate in-silico product ion peaklists for glycosphingolipids.
Lipid of the month
Chenodeoxycholic acid (3alpha,7alpha-dihydroxy-5ß-cholan-24-oic acid) is a C24 bile acid and one of the main bile acids produced by the liver. Chenodeoxycholic acid is synthesized in the liver from cholesterol and can be conjugated in the liver with taurine or glycine, forming taurochenodeoxycholic acid or glycochenodeoxycholic acid. Chenodeoxycholic acid is the most potent natural bile acid for stimulating the nuclear bile acid receptor, farnesoid X receptor. The transcription of many genes is activated by FXR.
Events calendar
-
September 15-16, 2016
Biophysical Society 61st Annual Meeting
February 11 - 15, 2017
Research library
-
Quantitative profiling of the endonuclear glycerophospholipidome of murine embryonic fibroblasts
J. Lipid Res. 2016 57:(8) 1492-1506. First Published on June 2, 2016, doi:10.1194/jlr.M068734