Research library - browse by date

This library is a growing collection of the most significant research advances and key review articles, categorized by subject areas, from across the literature.

  • February 2012

    • Two PI 3-Kinases and One PI 3-Phosphatase Together Establish the Cyclic Waves of Phagosomal PtdIns(3)P Critical for the Degradation of Apoptotic Cells

      Lu N., Shen Q., Mahoney T., Neukomm L., Wang Y. et al.

      PLoS Biology (Published online 17 January 2012)

      [doi: 10.1371/journal.pbio.1001245]

    • Enzymatic measurement of phosphatidylserine in cultured cells

      Morita S., Shirakawa S., Kobayashi Y., Nakamura K., Teraoka R. et al.

      Journal of Lipid Research 53, (2012)

      [doi: 10.1194/jlr.D021808]

    • Deleterious impact of elaidic fatty acid on ABCA1-mediated cholesterol efflux from mouse and human macrophages

      Fourniera N., Attia N., Rousseau-Ralliard D., Vedie B., Destaillats F. et al.

      Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1821, (2012)

      [doi: 10.1016/j.bbalip.2011.10.005]

    • Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1

      Kanter J., Kramer F., Barnhart S., Averill M., Vivekanandan-Giri A. et al.

      Proceedings of the National Academy of Sciences (Published online 17 January 2012)

      [doi: 10.1073/pnas.1111600109]

    • Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling

      Zhang C., Wendel A., Keogh M., Harris T., Chen J. et al.

      Proceedings of the National Academy of Sciences (Published online 17 January 2012)

      [doi: 10.1073/pnas.1110730109]

    • Serum amyloid A opposes lipoxin A4 to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease

      Bozinovski S., Uddin M., Vlahos R., Thompson M., McQualter J. et al.

      Proceedings of the National Academy of Sciences 109, (2012)

      [doi: 10.1073/pnas.1109382109]

    • Affinity of talin-1 for the β3-integrin cytosolic domain is modulated by its phospholipid bilayer environment

      Moore D., Nygren P., Jo H., Boesze-Battaglia K., Bennett J. et al.

      Proceedings of the National Academy of Sciences 109, (2012)

      [doi: 10.1073/pnas.1117220108]

    • The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques

      van Gils J., Derby M., Fernandes L., Ramkhelawon B., Ray T. et al.

      Nat Immunol (Published online 8 January 2012)

      [doi: 10.1038/ni.2205]

    • Murine bone marrow-derived macrophages differentiated with GM-CSF become foam cells by PI3Kγ-dependent fluid-phase pinocytosis of native LDL

      Anzinger J., Chang J., Xu Q., Barthwal M., Bohnacker T. et al.

      Journal of Lipid Research 53, (2012)

      [doi: 10.1194/jlr.M018887]

    • Quantitative analysis of the lipidomes of the influenza virus envelope and MDCK cell apical membrane

      Gerl M., Sampaio J., Urban S., Kalvodova L., Verbavatz J. et al.

      The Journal of Cell Biology (Published online 16 January 2012)

      [doi: 10.1083/jcb.201108175]

    • Identification of a new plasma biomarker of Alzheimer Disease using metabolomics technology

      Sato Y., Suzuki I., Nakamura T., Bernier F., Aoshima K. et al.

      Journal of Lipid Research (Published online 27 December 2011)

      [doi: 10.1194/jlr.M022376]

    • Dynamics of arachidonic acid mobilization by inflammatory cells

      Astudillo A., Balgoma D., Balboa M. and Balsinde J.

      Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1821, (2012)

      [doi: 10.1016/j.bbalip.2011.11.006]

    • Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice

      Panigrahy D., Edin M., Lee C., Huang S., Bielenberg D. et al.

      The Journal of Clinical Investigation 122, (2012)

      [doi: 10.1172/JCI58128]

    • A catalytically silent FAAH-1 variant drives anandamide transport in neurons

      Fu J., Bottegoni G., Sasso O., Bertorelli R., Rocchia W. et al.

      Nat Neurosci 15, 64 - 69 (2012)

      [doi: 10.1038/nn.2986]

    • Signal-dependent Hydrolysis of Phosphatidylinositol 4,5-Bisphosphate without Activation of Phospholipase C

      Lev S., Katz B., Tzarfaty V. and Minke B.

      Journal of Biological Chemistry 287, (2012)

      [doi: 10.1074/jbc.M111.266585]

    • Natural Diterpenoid Compound Elevates Expression of Bim Protein, Which Interacts with Antiapoptotic Protein Bcl-2, Converting It to Proapoptotic Bax-like Molecule

      Zhao L., He F., Liu H., Zhu Y., Tian W. et al.

      Journal of Biological Chemistry 287, (2012)

      [doi: 10.1074/jbc.M111.264481]

    • Oleosin Is Bifunctional Enzyme That Has Both Monoacylglycerol Acyltransferase and Phospholipase Activities

      Parthibane V., Rajakumari S., Venkateshwari V., Iyappan R. and Rajasekharan R.

      Journal of Biological Chemistry 287, (2012)

      [doi: 10.1074/jbc.M111.309955]

    • Apolipoprotein E Promotes β-Amyloid Trafficking and Degradation by Modulating Microglial Cholesterol Levels

      Lee C., Tse W., Smith J. and Landreth G.

      Journal of Biological Chemistry 287, (2012)

      [doi: 10.1074/jbc.M111.295451]

    • Star-PAP Control of BIK Expression and Apoptosis Is Regulated by Nuclear PIPKIα and PKCδ Signaling

      Li W., Laishram R., Ji Z., Barlow C., Tian B. et al.

      Molecular Cell 45, (2012)

      [doi: 10.1016/j.molcel.2011.11.017]

    • Primary amines protect against retinal degeneration in mouse models of retinopathies

      Maeda A., Golczak M., Chen Y., Okano K., Kohno H. et al.

      Nat Chem Biol (Published online 25 December 2011)

      [doi: 10.1038/nchembio.759]

    • Oxysterols are allosteric activators of the oncoprotein Smoothened

      Nachtergaele S., Mydock L., Krishnan K., Rammohan J., Schlesinger P. et al.

      Nat Chem Biol (Published online 8 January 2012)

      [doi: 10.1038/nchembio.765]

    • Structure of HDAC3 bound to co-repressor and inositol tetraphosphate

      Watson P., Fairall L., Santos G. and Schwabe J.

      Nature (Published online 9 January 2012)

      [doi: 10.1038/nature10728]

    • Molecular recognition of a single sphingolipid species by a protein's transmembrane domain

      Contreras F.-X., Ernst A., Haberkant P., Bjorkholm P., Lindahl E. et al.

      Nature (Published online 9 January 2012)

      [doi: 10.1038/nature10742]

    • Structural rearrangements underlying ligand-gating in Kir channels

      Wang S., Lee S., Heyman S., Enkvetchakul D. and Nichols C.

      Nat Commun 3, 617 (2012)

      [doi: 10.1038/ncomms1625]

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