Research library - browse by date

This library is a growing collection of the most significant research advances and key review articles, categorized by subject areas, from across the literature.

  • November 2011

    • Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

      Rayner K., Esau C., Hussain F., McDaniel A., Marshall S. et al.

      Nature 478, 404 - 407 (2011)

      [doi: 10.1038/nature10486]

    • LPA-producing enzyme PA-PLA1[alpha] regulates hair follicle development by modulating EGFR signalling

      Inoue A., Arima N., Ishiguro J., Prestwich G., Arai H. et al.

      EMBO J 30, 4248 - 4260 (2011)

      [doi: 10.1038/emboj.2011.296]

    • Chemical inhibitors of monogalactosyldiacylglycerol synthases in Arabidopsis thaliana

      Botté C., Deligny M., Roccia A., Bonneau A., Saïdani N. et al.

      Nat Chem Biol 7, 834 - 842 (2011)

      [doi: 10.1038/nchembio.658]

    • Introduction to Lipid Biochemistry, Metabolism, and Signaling

      Brown H.A. and Marnett L.

      Chemical Reviews 111, 5817 - 5820 (2011)

      [doi: 10.1021/cr200363s]

    • MALDI Imaging of Lipid Biochemistry in Tissues by Mass Spectrometry

      Zemski Berry K., Hankin J., Barkley R., Spraggins J., Caprioli R. et al.

      Chemical Reviews 111, 6491 - 6512 (2011)

      [doi: 10.1021/cr200280p] LIPID MAPS

    • Bioinformatics and Systems Biology of the Lipidome

      Subramaniam S., Fahy E., Gupta S., Sud M., Byrnes R. et al.

      Chemical Reviews 111, 6452 - 6490 (2011)

      [doi: 10.1021/cr200295k] LIPID MAPS

    • Sphingolipid and Glycosphingolipid Metabolic Pathways in the Era of Sphingolipidomics

      Merrill A.

      Chemical Reviews 111, 6387 - 6422 (2011)

      [doi: 10.1021/cr2002917] LIPID MAPS

    • Mammalian Triacylglycerol Metabolism: Synthesis, Lipolysis, and Signaling

      Coleman R. and Mashek D.

      Chemical Reviews 111, 6359 - 6386 (2011)

      [doi: 10.1021/cr100404w]

    • Exploring Protein Lipidation with Chemical Biology

      Hang H. and Linder M.

      Chemical Reviews 111, 6341 - 6358 (2011)

      [doi: 10.1021/cr2001977]

    • PPARs and Lipid Ligands in Inflammation and Metabolism

      Harmon G., Lam M. and Glass C.

      Chemical Reviews 111, 6321 - 6340 (2011)

      [doi: 10.1021/cr2001355] LIPID MAPS

    • Regulation of Mammalian Physiology, Development, and Disease by the Sphingosine 1-Phosphate and Lysophosphatidic Acid Receptors

      Blaho V. and Hla T.

      Chemical Reviews 111, 6299 - 6320 (2011)

      [doi: 10.1021/cr200273u]

    • Leukotriene Receptors

      Nakamura M. and Shimizu T.

      Chemical Reviews 111, 6231 - 6298 (2011)

      [doi: 10.1021/cr100392s]

    • Prostanoid Receptors

      Hirata T. and Narumiya S.

      Chemical Reviews 111, 6209 - 6230 (2011)

      [doi: 10.1021/cr200010h]

    • Regulation and Functions of Diacylglycerol Kinases

      Shulga Y., Topham M. and Epand R.

      Chemical Reviews 111, 6186 - 6208 (2011)

      [doi: 10.1021/cr1004106]

    • Phospholipase A2 Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention

      Dennis E., Cao J., Hsu Y., Magrioti V. and Kokotos G.

      Chemical Reviews 111, 6130 - 6185 (2011)

      [doi: 10.1021/cr200085w] LIPID MAPS

    • Mechanism of Activation and Inactivation of Gq/Phospholipase C-β Signaling Nodes

      Harden T.K., Waldo G., Hicks S. and Sondek J.

      Chemical Reviews 111, 6120 - 6129 (2011)

      [doi: 10.1021/cr200209p]

    • Phospholipase D: Enzymology, Functionality, and Chemical Modulation

      Selvy P., Lavieri R., Lindsley C. and Brown H.A.

      Chemical Reviews 111, 6064 - 6119 (2011)

      [doi: 10.1021/cr200296t] LIPID MAPS

    • The Metabolic Serine Hydrolases and Their Functions in Mammalian Physiology and Disease

      Long J. and Cravatt B.

      Chemical Reviews 111, 6022 - 6063 (2011)

      [doi: 10.1021/cr200075y]

    • Formation and Signaling Actions of Electrophilic Lipids

      Schopfer F., Cipollina C. and Freeman B.

      Chemical Reviews 111, 5997 - 6021 (2011)

      [doi: 10.1021/cr200131e]

    • Isoprostane Generation and Function

      Milne G., Yin H., Hardy K., Davies S. and Roberts L.J.

      Chemical Reviews 111, 5973 - 5996 (2011)

      [doi: 10.1021/cr200160h] LIPID MAPS

    • Resolvins and Protectins in Inflammation Resolution

      Serhan C. and Petasis N.

      Chemical Reviews 111, 5922 - 5943 (2011)

      [doi: 10.1021/cr100396c] LIPID MAPS

    • Endocannabinoid Oxygenation by Cyclooxygenases, Lipoxygenases, and Cytochromes P450: Cross-Talk between the Eicosanoid and Endocannabinoid Signaling Pathways

      Rouzer C. and Marnett L.

      Chemical Reviews 111, 5899 - 5921 (2011)

      [doi: 10.1021/cr2002799] LIPID MAPS

    • Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease

      Haeggström J. and Funk C.

      Chemical Reviews 111, 5866 - 5898 (2011)

      [doi: 10.1021/cr200246d]

    • Enzymes of the Cyclooxygenase Pathways of Prostanoid Biosynthesis

      Smith W., Urade Y. and Jakobsson P.

      Chemical Reviews 111, 5821 - 5865 (2011)

      [doi: 10.1021/cr2002992]

    • Introduction to Lipid Biochemistry, Metabolism, and Signaling

      Brown H.A. and Marnett L.

      Chemical Reviews 111, 5817 - 5820 (2011)

      [doi: 10.1021/cr200363s] LIPID MAPS

    • STED Nanoscopy Reveals Molecular Details of Cholesterol- and Cytoskeleton-Modulated Lipid Interactions in Living Cells

      Mueller V., Ringemann C., Honigmann A., Schwarzmann G., Medda R. et al.

      Biophysical Journal 101, (2011)

      [doi: 10.1016/j.bpj.2011.09.006]

    • Structural Basis for Activation and Inhibition of Class I Phosphoinositide 3-Kinases

      Vadas O., Burke J.E., Zhang X., Berndt A. and Williams R.L.

      Science Signaling 4, re2 (2011)

      [doi: 10.1126/scisignal.2002165]

    • Structural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensor

      Lu Q., Yu J., Yan J., Wei Z. and Zhang M.

      Molecular Biology of the Cell (Published online 30 September 2011)

      [doi: 10.1091/mbc.E11-04-0354]

    • c-Fos Activates and Physically Interacts with Specific Enzymes of the Pathway of Synthesis of Polyphosphoinositides

      Alfonso A., Cardozo A., Renner M., Molina-Calavita M. and Caputto B.

      Molecular Biology of the Cell (Published online 12 October 2011)

      [doi: 10.1091/mbc.E11-03-0259]

    • Presence, formation and putative biological activities of N-acyl serotonins, a novel class of fatty-acid derived mediators, in the intestinal tract

      Verhoeckx K., Voortman T., Balvers M., Hendriks H., Wortelboer H. et al.

      Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1811, (2011)

      [doi: 10.1016/j.bbalip.2011.07.008]

    • Enteral Omega-3 Fatty Acid, γ-Linolenic Acid, and Antioxidant Supplementation in Acute Lung Injury

      Rice T., Wheeler A., Thompson B., Deboisblanc B., Steingrub J. et al.

      JAMA: The Journal of the American Medical Association 306, (2011)

      [doi: 10.1001/jama.2011.1435]

    • (R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2

      Duggan K., Hermanson D., Musee J., Prusakiewicz J., Scheib J. et al.

      Nat Chem Biol (Published online 25 September 2011)

      [doi: 10.1038/nchembio.663]

    • Macrophage-mediated inflammation in metabolic disease

      Chawla A., Nguyen K. and Goh Y.P.S.

      Nat Rev Immunol (Published online 10 October 2011)

      [doi: 10.1038/nri3071]

    • Altered hepatic lipid metabolism in C57BL/6 mice fed alcohol: a targeted lipidomic and gene expression study

      Clugston R., Jiang H., Lee M., Piantedosi R., Yuen J. et al.

      Journal of Lipid Research 52, (2011)

      [doi: 10.1194/jlr.M017368]

    • Enzymological analysis of the tumor suppressor A-C1 reveals a novel group of phospholipid-metabolizing enzymes

      Shinohara N., Uyama T., Jin X., Tsuboi K., Tonai T. et al.

      Journal of Lipid Research 52, (2011)

      [doi: 10.1194/jlr.M015081]

    • Towards a whole-body systems [multi-organ] lipidomics in Alzheimer's disease

      Astarita G. and Piomelli D.

      Prostaglandins, Leukotrienes and Essential Fatty Acids 85, (2011)

      [doi: 10.1016/j.plefa.2011.04.021]

    • Dynamics of human adipose lipid turnover in health and metabolic disease

      Arner P., Bernard S., Salehpour M., Possnert G., Liebl J. et al.

      Nature 478, 110 - 113 (2011)

      [doi: 10.1038/nature10426]

    • Phosphatidylinositol(4,5)bisphosphate coordinates actin-mediated mobilization and translocation of secretory vesicles to the plasma membrane of chromaffin cells

      Wen P., Osborne S., Zanin M., Low P.C., Wang H. et al.

      Nat Commun 2, 491 (2011)

      [doi: 10.1038/ncomms1500]

    • Phosphatidylserine is polarized and required for proper Cdc42 localization and for development of cell polarity

      Fairn G.D., Hermansson M., Somerharju P. and Grinstein S.

      Nature Cell Biology (Published online 2 October 2011)

      [doi: 10.1038/ncb2351]

    • ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

      Murphy A., Akhtari M., Tolani S., Pagler T., Bijl N. et al.

      The Journal of Clinical Investigation 121, (2011)

      [doi: 10.1172/JCI57559]

    • Optic atrophy 1 is an A-kinase anchoring protein on lipid droplets that mediates adrenergic control of lipolysis

      Pidoux G., Witczak O., Jarnaess E., Myrvold L., Urlaub H. et al.

      EMBO J (Published online 7 October 2011)

      [doi: 10.1038/emboj.2011.365]

    • A High Content Drug Screen Identifies Ursolic Acid as an Inhibitor of Amyloid β Protein Interactions with Its Receptor CD36

      Wilkinson K., Boyd J., Glicksman M., Moore K. and El Khoury J.

      Journal of Biological Chemistry 286, (2011)

      [doi: 10.1074/jbc.M111.232116]

    • Altered Arachidonate Distribution in Macrophages from Caveolin-1 Null Mice Leading to Reduced Eicosanoid Synthesis

      Astudillo A., Perez-Chacon G., Meana C., Balgoma D., Pol A. et al.

      Journal of Biological Chemistry 286, (2011)

      [doi: 10.1074/jbc.M111.277137]

    • Binding of Autotaxin to Integrins Localizes Lysophosphatidic Acid Production to Platelets and Mammalian Cells

      Fulkerson Z., Wu T., Sunkara M., Kooi C., Morris A. et al.

      Journal of Biological Chemistry 286, (2011)

      [doi: 10.1074/jbc.M111.276725]

    • PI3Kγ within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance

      Becattini B., Marone R., Zani F., Arsenijevic D., Seydoux J. et al.

      Proceedings of the National Academy of Sciences 108, (2011)

      [doi: 10.1073/pnas.1106698108]

    • Furan fatty acid as an anti-inflammatory component from the green-lipped mussel Perna canaliculus

      Wakimoto T., Kondo H., Nii H., Kimura K., Egami Y. et al.

      Proceedings of the National Academy of Sciences (Published online 18 October 2011)

      [doi: 10.1073/pnas.1110577108]

    • Lateral sorting in model membranes by cholesterol-mediated hydrophobic matching

      Kaiser H., Orłowski A., Rog T., Nyholm T., Chai W. et al.

      Proceedings of the National Academy of Sciences 108, (2011)

      [doi: 10.1073/pnas.1103742108]

    • Inositol Polyphosphate 4-Phosphatase B as a Regulator of Bone Mass in Mice and Humans

      Ferron M., Boudiffa M., Arsenault M., Rached M., Pata M. et al.

      Cell Metabolism 14, (2011)

      [doi: 10.1016/j.cmet.2011.08.013]

    • Autophagy and Lipid Metabolism Coordinately Modulate Life Span in Germline-less C. elegans

      Lapierre L., Gelino S., Melendez A. and Hansen M.

      Current Biology 21, (2011)

      [doi: 10.1016/j.cub.2011.07.042]

    • OCRL controls trafficking through early endosomes via PtdIns4,5P2-dependent regulation of endosomal actin

      Vicinanza M., Di Campli A., Polishchuk E., Santoro M., Di Tullio G. et al.

      EMBO J (Published online 4 October 2011)

      [doi: 10.1038/emboj.2011.354]

    • Novel oxysterols observed in tissues and fluids of AY9944-treated rats: a model for Smith-Lemli-Opitz syndrome

      Xu L., Liu W., Sheflin L., Fliesler S. and Porter N.

      Journal of Lipid Research 52, (2011)

      [doi: 10.1194/jlr.M018366]

    • Metabolomics annotates ABHD3 as a physiologic regulator of medium-chain phospholipids

      Long J., Cisar J., Milliken D., Niessen S., Wang C. et al.

      Nat Chem Biol (Published online 18 September 2011)

      [doi: 10.1038/nchembio.659]

    • Apicobasal domain identities of expanding tubular membranes depend on glycosphingolipid biosynthesis

      Zhang H., Abraham N., Khan L., Hall D., Fleming J. et al.

      Nature Cell Biology (Published online 18 September 2011)

      [doi: 10.1038/ncb2328]

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