Lipidomics update - July 2011
The lipidomics update provides an overview of developments in lipid research. Each month we offer a fresh collection of research, news and events for the specialist and the interested non-specialist alike. Register for our email alert to stay informed.
Lipid of the month
Aldosterone
In addition to lowering blood pressure, new and existing drugs that target aldosterone might be useful for treating inflammation and insulin resistance.
Research highlights
Obesity and diabetes: An antidiabetic phospholipidDLPC improves insulin sensitivity and reduces fatty liver, in a mechanism involving the nuclear receptor LRH-1.
Lipid biosynthesis: Seek and ye shall findResearchers have found a key missing link in the mammalian phospholipid biosynthetic network — an unusual mitochondrial phosphatase, PTPMT1.
Signalling: PI3Kβ linking signals for neutrophil activationA new study suggests that PI3Kβ, rather than PI3Kγ, may be a more relevant therapeutic target in disorders involving immune complex deposition, such as rheumatoid arthritis.
Innate immunity: Linking lipids and inflammasomesNew research that the SREBP isoform SREBP1a links lipogenesis and inflammasome-mediated inflammatory responses in macrophages.
News
- Human cell becomes living laser
- Life hackers seek new tools
- Whistle-blower claims his accusations cost him his job
- Back to the bench
- Mobility rethought
Events calendar
FASEB Conference on Lysophospholipid Mediators in Health and Disease
14 - 19 August, 2011
Southeastern Regional Lipid Conference (SERLC)
9 - 11 November, 2011
Research library
- The outs and the ins of sphingosine-1-phosphate in immunity Nature Reviews Immunology
- Linking Lipid Metabolism to the Innate Immune Response in Macrophages through Sterol Regulatory Element Binding Protein-1a Cell Metabolism
- more from the research library
