Lipidomics update - June 2011
The lipidomics update provides an overview of developments in lipid research. Each month we offer a fresh collection of research, news and events for the specialist and the interested non-specialist alike. Register for our email alert to stay informed.
Lipid of the month
Lipoxin A4
This eicosanoid acts through multiple mechanisms to promote the resolution of inflammation and might provide the basis for therapeutics for several diseases.
Research Highlights
Cancer: Lipoxygenase makes a leaky tumourThe spread of mammary carcinoma from the primary tumour to consecutive lymph nodes requires the lipoxygenase-derived eicosanoid 12(S)-HETE.
LIPID MAPS 2011: Lipidomics deliversThis year's conference confirms that other fields are appreciating the importance of lipidomics.
Researchers have found a link between the innate immune response to infection and regulation of the sterol metabolic network characterized by down-regulation of sterol biosynthesis by an interferon regulatory loop mechanism.
Metabolism: Fight the fat, cure the (ER) stressChanges in lipid metabolism in obesity cause ER stress by interfering with protein folding through a mechanism involving lipids.
Bacterial physiology: Flipping lipidsThe mechanism underlying the translocation of lipid II across the membrane is mediated by the integral membrane protein FtsW.
Metabolism and infectionNews
- The Achilles' heel of biological complexity
- How to succeed with grant applications
- Stem cells: The growing pains of pluripotency
- Research beyond the recession
Events calendar
Gordon Research Conference on Molecular & Cellular Biology of Lipids
17 - 22 July, 2011
52nd International Conference on the Bioscience of Lipids
30 August - 3 September, 2011
Research library
- Lipidomics at the Interface of Structure and Function in Systems Biology Chemistry & Biology
- Imaging mass spectrometry for lipidomics Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- more from the research library
