Lipidomics update - December 2010
The lipidomics update provides an overview of developments in lipid research. Each month we offer a fresh collection of research, news and events for the specialist and the interested non-specialist alike. Register for our email alert to stay informed.
Lipid of the month
Resveratrol
After nearly two decades, researchers haven't lost their appetite for studying the potential health benefits of this naturally occurring polyphenol, most famously found in red wine.
Research highlights
Lipids in inflammation: Driving autophagyDe novo sphingolipid synthesis is essential for autophagy.
Lipids in immunity: Statins set up bacterial trapsBy modulating sterol synthesis, statins help the immune system fight infection by increasing the number of microbial extracellular traps.
Innate immunity: A new vein of TLR biologyInflammation leads to the release of oxidized phospholipids that drive angiogenesis by activating Toll-like receptor 2 (TLR2) on endothelial cells.
Endocannabinoids: Dual effects at different sitesEndocannabinoid activation of astrocytic CB1Rs potentiates neurotransmission at synapses far away from the site of endocannabinoid release.
Rheumatoid arthritis: Can statin use help prevent RA onset?A large retrospective analysis suggests that persistent statin use may have a protective effect against RA.
News
- Good news for 'good' cholesterol
- Study says middle sized labs do best
- No rest for the bio-wikis
- MicroRNAs mediate an early birth
- Decisions hint that not all biologics are created with equal ease
Events calendar
Research library
- Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands Nature
- Inhibition of ceramide biosynthesis preserves photoreceptor structure and function in a mouse model of retinitis pigmentosa Proceedings of the National Academy of Sciences
- more from the research library
