Lipidomics update - November 2010
The lipidomics update provides an overview of developments in lipid research. Each month we offer a fresh collection of research, news and events for the specialist and the interested non-specialist alike. Register for our email alert to stay informed.
Lipid of the month
Myriocin
The fungal metabolite from which fingolimod — a pioneering oral disease-modifying multiple sclerosis drug — was derived.
Research highlights
Mouse macrophage lipids: All systems goBy combining lipidomic with transcriptomic methods, researchers have uncovered a whole-system picture of immunologically- and pharmacologically-induced lipid perturbations in mouse macrophages.
Synaptic size regulation: Tweeking PI to get a boutonBy controlling the localization of an actin-binding protein, PI(4,5)P2 controls synapse growth in Drosophila.
Bacterial physiology: Bacterial lipid rafts discoveredIdentification of bacterial lipid rafts that coordinate signalling pathways and regulate biofilm formation in Bacillus subtilis.
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Influenza virus M2 protein mediates ESCRT-independent membrane scission.
Cytoskeleton: Filopodia self-assembleIn vitro model system of self-assembly of filopodia-like structures on supported lipid bilayers enriched in phosphatidylinositol (4,5)-bisphosphate.
Virology: Severing the budNews
- Fat fathers affect daughters' health
- The renegade gene test
- China's $2.4 billion splurge
- Call for renewed focus on rare mutations grows more common
- US midterm elections: NIH prepares for loss of political champions
Events calendar
Research library
- Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor Nature
- Incorporation profiles of conjugated linoleic acid isomers in cell membranes and their positional distribution in phospholipids Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- more from the research library
