Lipidomics update - October 2010
The lipidomics update provides an overview of developments in lipid research. Each month we offer a fresh collection of research, news and events for the specialist and the interested non-specialist alike. Register for our email alert to stay informed.
Lipid of the month
α-tocopherol
The most bioavailable—and most studied—of the Vitamin E subclass of prenol lipids, α-tocopherol is a chain-breaking antioxidant.
Research highlights
Human plasma lipids: The alpha to omegaOver 500 lipid species have been identified and quantified in human blood plasma.
COX inhibition: Naproxen by proxyStructural basis of COX inhibition suggests that adverse effects of NSAIDs will not be easily avoided.
Glycosylation defects: To add sugar, reduce fatSRD5A3 catalyzes a reduction step in the synthesis of precursors for N-glycosylation, and is mutated in congenital disorders of glycosylation.
Bacterial pathogenesis: Messing up the membraneVibrio parahaemolyticus VPA0450 contributes to host cell death by interfering with phosphatidylinositol signaling.
Bacterial physiology: Bacillus takes the temperatureBacillus subtilis uses a ruler-like mechanism to sense temperature according to membrane thickness.
News
- Tiny traits cause big headaches
- Theory is acid test for fructose's blood pressure role
- Oil-spill bacteria gobbled gases first
- Getting a better grip on lab mice
- Amidst growing vaccine concerns, NIH sets up engine for answers
Events calendar
Research library
- GPR120 Is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects Cell
- 12/15-lipoxygenase–derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases Proceedings of the National Academy of Sciences
- more from the research library
