Lipidomics update - February 2010
The lipidomics update provides an overview of developments in lipid research. Each month we offer a fresh collection of research, news and events for the specialist and the interested non-specialist alike. Register for our email alert to stay informed.
Lipid of the month
2-Arachidonoylglycerol
Endocannabinoids, including 2-arachidonoylglycerol (2-AG), are endogenous lipid mediators that activate the cannabinoid receptors.
Research highlights
Immune response: Oxysterol takes Toll on IgALipidomic study reveals that secretion of 25-hydroxycholesterol by macrophages regulates the adaptive immune response.
Cancer: Growing on a free-fat dietHigh expression of a lipid-hydrolyzing enzyme in aggressive cancer generates free fatty acids and fuels oncogenic lipid-signaling pathways.
Lipid trafficking: Exchange by ORDerORPs bind two membranes simultaneously and regulate sterol transfer between them.
Viral infection: Entry through tunnel visionSV40 induces the formation of tubular invaginations in the host cell membrane in a manner that is dependent on the acyl-chain length of GM1 but independent of active host cell trafficking machinery.
News
- Health benefits of red-wine chemical unclear
- 'Big science' spurs collaborative trend
- Why oil from the Exxon Valdez lingers
- Bisphenol A link to heart disease confirmed
- Chemists crack complex compound
Events calendar
51st ICBL 2010 - International Conference on the Bioscience of Lipids
7 - 11 September, 2010
Cancer & Obesity - IASO Hot Topic Conference
28 - 30 October, 2010
Research library
- A novel form of Total Internal Reflection Fluorescence Microscopy (LG-TIRFM) reveals different and independent lipid raft domains in living cells Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- The p110-delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors Nature Chemical Biology
- more from the research library
