Research library - browse by date
This library is a growing collection of the most significant research advances and key review articles, categorized by subject areas, from across the literature.
May 2009
Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL
Brown M. S. and Goldstein J. L.
Journal of Lipid Research
Cardiomyopathies: The fatty hearts of patients with diabetes
Lingvay Ildiko, Raskin Philip and Szczepaniak Lidia S.
Nature Reviews Cardiology
Getting a handle on protein prenylation
Hougland James L and Fierke Carol A
Nature Chemical Biology
Obesity: Be cool, lose weight
Farmer Stephen R.
Nature
Statins Impair CD1d-Mediated Antigen Presentation through the Inhibition of Prenylation
Khan M. A. et al.
The Journal of Immunology
Sequential Regulation of DOCK2 Dynamics by Two Phospholipids During Neutrophil Chemotaxis
Nishikimi A. et al.
Science
Cell Biology: Two lipids that give direction
Cote J.-F. and Vuori K.
Science
Cell Biology: Ceramides--Friend or Foe in Hypoxia?
Crowder C. M.
Science
Natural Lipid Ligands Associated with Human CD1d Targeted to Different Subcellular Compartments
Yuan W., Kang S.-J., Evans J. E. and Cresswell P.
The Journal of Immunology
Molecular Mechanism of Apolipoprotein E Binding to Lipoprotein Particles†
Nguyen David, Dhanasekaran Padmaja, Phillips Michael C. and Lund-Katz Sissel
Biochemistry
Twist-1 Is a PPARδ-Inducible, Negative-Feedback Regulator of PGC-1α in Brown Fat Metabolism
Pan Dongning, Fujimoto Masaki, Lopes Andrea and Wang Yong-Xu
Cell
MUC1-induced alterations in a lipid metabolic gene network predict response of human breast cancers to tamoxifen treatment
Pitroda S. P. et al.
Proceedings of the National Academy of Sciences
Curvature-driven lipid sorting needs proximity to a demixing point and is aided by proteins
Sorre B. et al.
Proceedings of the National Academy of Sciences
A scissors mechanism for stimulation of SNARE-mediated lipid mixing by cholesterol
Tong J., Borbat P. P., Freed J. H. and Shin Y.-K.
Proceedings of the National Academy of Sciences
Oxidized LDL impair adipocyte response to insulin by activating serine/threonine kinases
Scazzocchio B. et al.
Journal of Lipid Research
LCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteins
Hirsch-Reinshagen V. et al.
Journal of Lipid Research
Phenolic acids suppress adipocyte lipolysis via activation of the nicotinic acid receptor GPR109A (HM74a/PUMA-G)
Ren N. et al.
Journal of Lipid Research
Mitochondria do not contain lipid rafts, and lipid rafts do not contain mitochondrial proteins
Zheng Y. Z., Berg K. B. and Foster L. J.
Journal of Lipid Research
Cholesterol depletion associated with Leishmania major infection alters macrophage CD40 signalosome composition and effector function
Rub Abdur et al.
Nature Immunology
Analysis of the eukaryotic prenylome by isoprenoid affinity tagging
Nguyen Uyen T T et al.
Nature Chemical Biology
Autophagy regulates lipid metabolism
Singh Rajat et al.
Nature
The impact of the metabolic syndrome and its components on the incidence of ischemic heart disease and stroke: the Japan public health center-based study
Noda Hiroyuki et al.
Hypertension Research
Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine: a novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals
Zitomer N. C. et al.
The Journal of Biological Chemistry
Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy
ZHENG W et al.
Biochimica et Biophysica Acta
Depth resolution during C60+ profiling of multilayer molecular films
Zheng Leiliang, Wucher Andreas and Winograd Nicholas
Analytical Chemistry
Analysis of polyunsaturated aminophospholipid molecular species using isotope-tagged derivatives and tandem mass spectrometry/mass spectrometry/mass spectrometry
ZEMSKIBERRY K and MURPHY R
Analytical Biochemistry
Analysis of cell membrane aminophospholipids as isotope-tagged derivatives
Berry K. A. Z.
Journal of Lipid Research
Mutation of beta-glucosidase 2 causes glycolipid storage disease and impaired male fertility
Yildiz Yildiz et al.
The Journal of Clinical Investigation
Sterol intermediates from cholesterol biosynthetic pathway as liver X receptor ligands
Yang C.
The Journal of Biological Chemistry
An undecaprenyl phosphate-aminoarabinose flippase required for polymyxin resistance in Escherichia coli
Yan A., Guan Z. and Raetz C. R. H.
The Journal of Biological Chemistry
Identification and quantification of dolichol and dolichoic acid in neuromelanin from substantia nigra of the human brain
Ward W. C. et al.
Journal of Lipid Research
Identification of Undecaprenyl Phosphate-beta-d-Galactosamine in Francisella novicida and Its Function in Lipid A Modification (dagger)
Wang Xiaoyuan, Ribeiro Anthony A., Guan Ziqiang and Raetz Christian R. H.
Biochemistry
Structure and biosynthesis of free lipid A molecules that replace lipopolysaccharide in Francisella tularensis subsp. novicida
Wang Xiaoyuan et al.
Biochemistry
Attenuated virulence of a Francisella mutant lacking the lipid A 4'-phosphatase
Wang X. et al.
Proceedings of the National Academy of Sciences
N-(4-Hydroxyphenyl)retinamide increases dihydroceramide and synergizes with dimethylsphingosine to enhance cancer cell killing
Wang H. et al.
Molecular Cancer Therapeutics
Steroidogenic factor-1 is a sphingolipid binding protein
Urs Aarti N. et al.
Molecular and Cellular Endocrinology
Elucidation of Double Bond Position in Unsaturated Lipids by Ozone Electrospray Ionization Mass Spectrometry
Thomas Michael C. et al.
Analytical Chemistry
FcεRI and Thy-1 domains have unique protein and lipid compositions
Surviladze Z., Harrison K. A., Murphy R. C. and Wilson B. S.
Journal of Lipid Research
LMSD: LIPID MAPS structure database
Sud M. et al.
Nucleic Acids Research
Quantitation of cardiolipin molecular species in spontaneously hypertensive heart failure rats using electrospray ionization mass spectrometry
Sparagna G. C.
Journal of Lipid Research
Loss of cardiac tetralinoleoyl cardiolipin in human and experimental heart failure
Sparagna G. C. et al.
Journal of Lipid Research
Biosynthesis of Undecaprenyl Phosphate-Galactosamine and Undecaprenyl Phosphate-Glucose in Francisella novicida (dagger)
Song Feng, Guan Ziqiang and Raetz Christian R. H.
Biochemistry
Regulation of macrophage function in inflammation and atherosclerosis
Shibata N. and Glass C. K.
Journal of Lipid Research
Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers
Shaner R. L. et al.
Journal of Lipid Research
Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily
Schaaf Gabriel et al.
Molecular Cell
Crystallization and preliminary X-ray diffraction analysis of phospholipid-bound Sfh1p, a member of the Saccharomyces cerevisiae Sec14p-like phosphatidylinositol transfer protein family
Schaaf Gabriel et al.
Acta Crystallographica
Lipid profiling reveals arachidonate deficiency in RAW264.7 cells: Structural and functional implications
Rouzer Carol A. et al.
Biochemistry
Lipid profiling reveals glycerophospholipid remodeling in zymosan-stimulated macrophages
Rouzer Carol A. et al.
Biochemistry
Glucosylceramide synthase is an essential regulator of pathogenicity of Cryptococcus neoformans
Rittershaus P. C.
The Journal of Clinical Investigation
Ceramide transfer protein function is essential for normal oxidative stress response and lifespan
Rao R. P. et al.
Proceedings of the National Academy of Sciences
Discovery of new biosynthetic pathways: the lipid A story
Raetz C. R. H. et al.
Journal of Lipid Research
Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4
Raetz C. R. H.
Journal of Lipid Research
On the biogenesis of lipid bodies in ancient eukaryotes: synthesis of triacylglycerols by a Toxoplasma DGAT1-related enzyme
Quittnat Friederike et al.
Molecular and Biochemical Parasitology
Lipidomics analysis of essential fatty acids in macrophages
QUEHENBERGER O et al.
Prostaglandins, Leukotrienes, and Essential Fatty Acids
Electrospray mass spectrometry of phospholipids
Pulfer Melissa and Murphy Robert C.
Mass Spectrometry Reviews
Biodiversity of sphingoid bases ("sphingosines") and related amino alcohols
Pruett S. T. et al.
Journal of Lipid Research
Reconstruction of cellular signalling networks and analysis of their properties
Papin Jason A., Hunter Tony, Palsson Bernhard O. and Subramaniam Shankar
Nature Reviews Molecular Cell Biology
Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP
Ortlund Eric A et al.
Nature Structural & Molecular Biology
Molecular determinants of crosstalk between nuclear receptors and toll-like receptors
Ogawa Sumito et al.
Cell
Cytoplasmic remodeling of erythrocyte raft lipids during infection by the human malaria parasite Plasmodium falciparum
Murphy S. C. et al.
Blood
Mass spectrometry advances in lipidomica: collision-induced decomposition of Kdo2-lipid A
MURPHY R, RAETZ C, REYNOLDS C and BARKLEY R
Prostaglandins & Other Lipid Mediators
Detection of the abundance of diacylglycerol and triacylglycerol molecular species in cells using neutral loss mass spectrometry
MURPHY R et al.
Analytical Biochemistry
Imaging of lipid species by MALDI mass spectrometry
Murphy R. C., Hankin J. A. and Barkley R. M.
Journal of Lipid Research
Electrospray ionization and tandem mass spectrometry of eicosanoids
MURPHY R et al.
Analytical Biochemistry
Lipidomics: an analysis of cellular lipids by ESI-MS
MILNE S, IVANOVA P, FORRESTER J and ALEXBROWN H
Methods
A targeted mass spectrometric analysis of phosphatidylinositol phosphate species
Milne S. B.
Journal of Lipid Research
Dramatic differences in the roles in lipid metabolism of two isoforms of diacylglycerol kinase
Milne Stephen B. et al.
Biochemistry
(Glyco)sphingolipidology: an amazing challenge and opportunity for systems biology
MERRILLJR A, WANG M, PARK M and SULLARDS M
Trends in Biochemical Sciences
Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry
MERRILLJR A et al.
Methods
Sphingolipidomics: a valuable tool for understanding the roles of sphingolipids in biology and disease
Merrill A. H. et al.
Journal of Lipid Research
A slow, tight-binding inhibitor of the zinc-dependent deacetylase LpxC of lipid A biosynthesis with antibiotic activity comparable to ciprofloxacin
McClerren Amanda L. et al.
Biochemistry
Direct qualitative analysis of triacylglycerols by electrospray mass spectrometry using a linear ion trap
MCANOY A, WU C and MURPHY R
Journal of the American Society for Mass Spectrometry
A kinetic model for calcium dynamics in RAW 264.7 cells: 1. mechanisms, parameters, and subpopulational variability
MAURYA M and SUBRAMANIAM S
Biophysical Journal
Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity
Marlo J. E. et al.
Molecular Pharmacology
Human cytomegalovirus regulates bioactive sphingolipids
Machesky N. J. et al.
The Journal of Biological Chemistry
SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism
Maceyka M.
The Journal of Biological Chemistry
Functional characterization of the promoter for the mouse SPTLC2 gene, which encodes subunit 2 of serine palmitoyltransferase
LINN S et al.
FEBS Letters
Ceramide kinase uses ceramide provided by ceramide transport protein: localization to organelles of eicosanoid synthesis
Lamour N. F. et al.
Journal of Lipid Research
Quorum-sensing signal synthesis by the Yersinia pestis acyl-homoserine lactone synthase YspI
Kirwan J. P. et al.
Journal of Bacteriology
N-(3-hydroxyhexanoyl)-L-homoserine lactone is the biologically relevant quormone that regulates the phz operon of Pseudomonas chlororaphis strain 30-84
Khan S. R. et al.
Applied and Environmental Microbiology
Dodecaprenyl phosphate-galacturonic acid as a donor substrate for lipopolysaccharide core glycosylation in Rhizobium leguminosarum
Kanjilal-Kolar S.
The Journal of Biological Chemistry
Expression cloning of three Rhizobium leguminosarum lipopolysaccharide core galacturonosyltransferases
Kanjilal-Kolar S.
The Journal of biological chemistry
A macrophage cell model for selective metalloproteinase inhibitor design
Jacobsen Faith E., Buczynski Matthew W., Dennis Edward A. and Cohen Seth M.
Chembiochem : a European journal of chemical biology
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
Inagaki Takeshi et al.
Cell metabolism
Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
Hevener Andrea L. et al.
The Journal of Clinical Investigation
Quantitation of fatty acyl-coenzyme A imolecular species in mammalian cells by liquid chromatography-electrospray ionization tandem mass spectrometry.
Haynes C. A. et al.
Journal of Lipid Research
Cholesteryl ester hydroperoxides are biologically active components of minimally oxidized LDL
Harkewicz R. et al.
Journal of Biological Chemistry
Arachidonate-derived dihomo-prostaglandin production observed in endotoxin stimulate macrophage-like cells
Harkewicz R., Fahy E., Andreyev A. and Dennis E. A.
The Journal of Biological Chemistry
Sublimation as a method of matrix application for mass spectrometric imaging
Hankin Joseph A., Barkley Robert M. and Murphy Robert C.
Journal of the American Society for Mass Spectrometry
Subcellular origin of sphingosine-1-phosphate is essental for its toxic effect in lyase deficient neurons
Hagen N. et al.
The Journal of Biological Chemistry
Identification of N-acylphosphatidylserine molecules in eukaryotic cells
Guan Ziqiang et al.
Biochemistry
Extraction and identification by mass spectrometry of undecaprenyl diphosphate-MurNAc-pentapeptide-GlcNAc from Escherichia coli
GUAN Z, BREAZEALE S and RAETZ C
Analytical Biochemistry
Dolichyl-phosphate-glucose is used to make O-glycans on glycoproteins of Trichomonas vaginalis
Grabinska K. A. et al.
Eukaryotic Cell
Specificity of acyl-homoserine lactone synthases examined by mass spectrometry
Gould T. A. et al.
Journal of Bacteriology
Combinatorial roles of nuclear receptors in inflammation and immunity
Glass Christopher K. and Ogawa Sumito
Nature Reviews Immunology
Going nuclear in metabolic and cardiovascular disease
Glass C. K.
The Journal of Clinical Investigation.
Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide
Giussani P. et al.
Molecular and Cellular Biology
An Inner Membrane Dioxygenase that Generates the 2-Hydroxymyristate Moiety of Salmonella Lipid A
Gibbons Henry S., Reynolds C. Michael, Guan Ziqiang and Raetz Christian R. H.
Biochemistry
Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma
GHISLETTI S et al.
Molecular Cell
Internal energy of molecules ejected due to energetic C(60) bombardment.
Garrison Barbara J. et al.
Analytical Chemistry
Identification of phosphatidylserylglutamtate: A novel minor lipid in Escherichia coli
Garrett T. A. et al.
Journal of Lipid Research
Sphingomyelinase restricts the lateral diffusion of CD4 and inhibits human immunodeficiency virus fusion
Finnegan C. M. et al.
Journal of Virology
Formation of eicosanoids, E2/D2 isoprostanes, and docosanoids following decapitation-induced ischemia, measured in high-energy-microwaved rat brain
Farias S. E. et al.
Journal of Lipid Research
LIPID MAPS online tools for lipid research
Fahy E., Sud M., Cotter D. and Subramaniam S.
Nucleic Acids Research
Update of the LIPID MAPS comprehensive classification system for lipids
Fahy E. et al.
Journal of Lipid Research
A comprehensive classification system for lipids
Fahy E.
Journal of Lipid Research
Effects of sphingosine-1-phosphate and ceramide-1-phosphate on rat intestinal smooth muscle cells: implications for postoperative ileus
Dragusin M.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Lipidomics joins the omics evolution
Dennis E. A.
Proceedings of the National Academy of Sciences
Acid sphingomyelinase deficiency prevents diet-induced hepatic triacylglycerol accumulation and hyperglycemia in mice
Deevska G. M. et al.
The Journal of Biological Chemistry
Liver X receptors regulate adrenal cholesterol balance
Cummins C. L.
The Journal of Clinical Investigation
Phosphatidylcholine and N-methylated phospholipids are nonessential in Saccharomyces cerevisiae
Choi J.-Y.
The Journal of Biological Chemistry
Linoleate-rich high-fat diet decreases mortality in hypertensive heart failure rats compared with lard and low-fat diets
Chicco A. J. et al.
Hypertension
Pulmonary surfactant proteins and lipids as modulators of inflammation and innate immunity
CHIBA Hirofumi et al.
Respirology
Quantification of diacylglycerol species from cellular extracts by electrospray ionization mass spectrometry using a linear regression algorithm
Callender Hannah L. et al.
Analytical Chemistry
TLR-4 and sustained calcium agonists synergistically produce eicosanoids independent of protein synthesis in RAW264.7 cells.
Buczynski M. W. et al.
The Journal of Biological Chemistry
An integrated omics analysis of eicosanoid biology
Buczynski M. W., Dumlao D. S. and Dennis E. A.
Journal of Lipid Research
A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes.
Zoncu Roberto et al.
Cell
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