Contact | Discussion | News | Publications | Site Map
	LIPID Metabolites And Pathways Strategy

About Lipid Classification Standards Experimental Data Databases Pathways Tools Protocols Home

LIPID MAPS Publications

Book Chapters

2007

Methods in Enzymology, Academic Press, Vol 432

New! Download all LIPID MAPS Methods in Enzymology Vol 432 Chapters as a single PDF.

Deems, R. A., Buczynski, M. W., Bowers-Gentry, R. C., Harkewicz, R., and Dennis, E. A. (2007) Detection and Quantitation of Eicosanoids via High Performance Liquid Chromatography/Electrospray Ionization Mass Spectrometry. in Meth. Enzymol., Academic Press, 432, 59-82.

Fahy, E., D. Cotter, R. Byrnes, M. Sud, A. Maer, J. Li, D. Nadeau, Y. Zhou, and S. Subramaniam. Bioinformatics for Lipidomics (2007). Meth. Enzymol. (432), 247-273.

Garrett, T. A., Guan, Z., and Raetz, C. R. (2007) Analysis of ubiquinones, dolichols and dolichol diphosphate-oligosaccharides by liquid chromatography-electrospray ionization mass spectrometry. in Meth. Enzymol., Academic Press, 432, 117-142.

Ivanova, P., Milne, S., Byrne, M. O., Xiang, Y., and Brown, H. A. (2007) Glycerophospholipid identification and quantitation by electrospray mass spectrometry. in Meth. Enzymol., Academic Press, 432, 21-57.

Krank, J., Murphy, R. C., Barkley, R. M., Duchoslav, E., and McAnoy, A. (2007) Qualitative analysis and quantitative assessment of changes in neutral glycerol lipid molecular species within cells. in Meth. Enzymol., Academic Press, 432, 1-20.

McDonald, J. G., Thompson, B., McCrum, E. C., and Russell, D. W. (2007) Extraction and analysis of sterols in biological matrices by high-performance liquid chromatography electrospray ionization mass spectrometry. in Meth. Enzymol., Academic Press, 432, 143-168.

Moore, J. D., Caufield, W. V., and Shaw, W. (2007) Quantitation and standardization of lipid internal standards for mass spectroscopy. in Meth. Enzymol., Academic Press, 432, 351-367.

Schmelzer, K., Fahy, E., Deems, R., Subramaniam, S., and Dennis, E. A. (2007) The Lipid Maps Initiative in Lipidomics. in Meth. Enzymol., Academic Press, 432, 169-181.

Sullards, M. C., Allegood, J. C., Kelly, S., Wang, E., Haynes, C. A., Park, H., Chen, Y., Shaner, R., and Merrill, A. H., Jr. (2007) Structure-specific, quantitative methods for analysis of sphingolipids by liquid-chromatography tandem mass spectrometry: "Inside-out" sphingolipidomics. in Meth. Enzymol., Academic Press, 432, 83-115.

Methods in Enzymology, Academic Press, Vol 433

Garrett, T. A., Kordestani, R., and Raetz, C. R. (2007) Quantification of cardiolipin by liquid chromatography-electrospray ionization mass spectrometry. in Meth. Enzymol., Academic Press, 433, 213-230.

Methods in Enzymology, Academic Press, Vol 434

Brown, H. A., Henage, L. G., Preininger, A. M., Xiang, Y., and Exton, J. H. (2007) Biochemical analysis of phospholipase D. in Meth. Enzymol., Academic Press, 434, 49-87.

Maurya, M. R., Benner,C., Pradervand,S., Glass,C. and Subramaniam,S. (2007) Systems Biology of Macrophages in Current Topics in Innate Immunity, Ed. J.D. Lambris. Pp. 62-79. Springer, New York.

Murphy, R. C., Fitzgerald, M., and Barkley, R. M. (2007) Neutral lipidomics and mass spectrometry, in Metabolomics, Metabonomics and Metabolite Profiling (Biomolecular Science series) Griffiths, W. ed., RSC Publishing, London, 161-189.

Peer Reviewed Journal Articles

2008

Chen, Y., Allegood, J. C., Liu, Y., Wang, E., Cox, T. M., Merrill, A. H., Jr., and Sullards, M. C., (2008) Imaging MALDI mass spectrometry using an oscillating capillary nebulizer matrix coating system and its application to analysis of lipids in brain from a mouse model of Tay-Sachs/Sandhoff disease, Anal Chem, in press.

Gibbons, H. S., Reynolds, C. M., Guan, Z., and Raetz, C. R., (2008) An inner membrane dioxygenase that generates the 2-hydroxymyristate moiety of Salmonella lipid A, Biochemistry, Epub ahead of publication.
PubMed ID: 18254598

Harkewicz, R., Hartvigsen, K., Almazan, F., Dennis, E. A., Witztum, J. L., and Miller, Y. I., (2008) Cholesteryl ester hydroperoxides are biologically active components of minimally oxidized LDL, J Biol Chem, Epub ahead of publication.
http://www.jbc.org/cgi/content/abstract/M709006200v1

Haynes, C. A., Allegood, J. C., Sims, K., Wang, E., Sullards, M. C., and Merrill, A. H., Jr., (2008) Quantitation of fatty acyl-coenzyme A molecular species in mammalian cell extracts by liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI MS/MS), J Lipid Res, Epub ahead of publication.
http://www.jlr.org/cgi/content/abstract/D800001-JLR200v1

Hutchins, P., and Murphy, R. C., (2008) Separation of cellular non–polar neutral lipids by normal phase chromatography and analysis by electrospray ionization mass spectrometry, J Lipid Res, Epub ahead of publication.
http://www.jlr.org/cgi/content/abstract/M700521-JLR200v1

Sasaki, H., and White, S. H., (2008) Aggregation behavior of an ultra-pure lipopolysaccharide (LPS) that stimulates TLR-4 receptors, Biophys J, in press.

Schaaf, G., Ortlund, E. A., Tyeryar, K. R., Mousley, C. J., Ile, K. E., Garrett, T. A., Ren, J., Woolls, M. J., Raetz, C. R., Redinbo, M. R., and Bankaitis, V. A., (2008) Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily, Mol Cell, 29, 191-206.
PubMed ID: 18243114

2007

Buczynski, M. W., Stephens, D. L., Bowers-Gentry, R. C., Grkovich, A., Deems, R. A., and Dennis, E. A. (2007) TLR-4 and sustained calcium agonists synergistically produce eicosanoids independent of protein synthesis in RAW264.7 cells., J Biol Chem, 282, 22834-22847.
PubMed ID: 17535806.

Byrnes, R. W., Fahy, E., and Subramaniam, S., (2007) A laboratory information management system for high throughput experimental lipidomics: minimal information required for the analysis of lipidomics experiments (MIALE) J. Assoc. Laboratory Automation, 12, 230-238.
http://www.jalajournal.com/article/S1535-5535(07)00106-2/abstract

Callender, H. L., Forrester, J. S., Ivanova, P., Preininger, A., Milne, S., and Brown, H. A. (2007) Quantification of diacylglycerol species from cellular extracts by electrospray ionization mass spectrometry using a linear regression algorithm, Anal Chem, 79, 263-272.
PubMed ID: 17194150.

Fahy, E., Sud, M., Cotter, D., and Subramaniam, S. (2007) LIPID MAPS online tools for lipid research, Nucleic Acids Res, 35, W606-W612.
PubMed ID: 17584797.

Finnegan, C. M., Rawat, S. S., Cho, E. H., Guiffre, D. L., Lockett, S., Merrill, A. H., Jr., and Blumenthal, R. (2007) Sphingomyelinase restricts the lateral diffusion of CD4 and inhibits human immunodeficiency virus fusion, J Virol, 81, 5294-5304.
PubMed ID: 17344303.

Fitzgerald, M., and Murphy, R. C. (2007) Electrospray mass spectrometry of human hair wax esters, J Lipid Res, 48, 1231-1246.
PubMed ID: 17277382.

Ghisletti, S., Huang, W., Ogawa, S., Pascual, G., Lin, M. E., Willson, T. M., Rosenfeld, M. G., and Glass, C. K. (2007) Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma, Mol Cell, 25, 57-70.
PubMed ID: 17218271.

Guan, Z., Li, S., Smith, D. C., Shaw, W. A., and Raetz, C. R. (2007) Identification of N-acylphosphatidylserine molecules in eukaryotic cells, Biochemistry, 46, 14500-14513.
PubMed ID: 18031065.

Hankin, J., Barkley, R. M., and Murphy, R. C. (2007) Sublimation as a method of matrix application for mass spectrometric imaging, J Am Soc Mass Spectrom, 18, 1646-1652.
PubMed ID: 17659880.

Harkewicz, R., Fahy, E., Andreyev, A., and Dennis, E. A. (2007) Arachidonate Derived Dihomo-prostaglandin Production Observed in Endotoxin Stimulate Macrophage-like Cells, J Biol Chem, 282, 2899-2910.
PubMed ID: 17135246.

Hevener, A. L., Olefsky, J. M., Reichart, D., Nguyen, M. T., Bandyopadyhay, G., Leung, H. Y., Watt, M. J., Benner, C., Febbraio, M. A., Nguyen, A. K., Folian, B., Subramaniam, S., Gonzalez, F. J., Glass, C. K., and Ricote, M. (2007) Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones, J Clin Invest, 117, 1658-1669.
PubMed ID: 17525798.

Khan, S. R., Herman, J., Krank, J., Serkova, N. J., Churchill, M. E., Suga, H., and Farrand, S. K., (2007) N-(3-Hydroxyhexanoyl)-l-homoserine lactone is the biologically relevant quormone that regulates the phz operon of Pseudomonas chlororaphis strain 30-84, Appl Environ Microbiol, 73, 7443-7455.
PubMed ID: 17921283

Lamour, N. F., Stahelin, R. V., Wijesinghe, D. S., Maceyka, M., Wang, E., Allegood, J. C., Merrill, A. H., Jr., Cho, W., and Chalfant, C. E. (2007) Ceramide kinase uses ceramide provided by ceramide transport protein: localization to organelles of eicosanoid synthesis, J Lipid Res, 48, 1293-1304.
PubMed ID: 17392267.

Maurya, M. R., and Subramaniam, S. (2007) A Kinetic Model for Calcium Dynamics in RAW 264.7 Cells: 1. Mechanisms, Parameters, and Subpopulational Variability, Biophys J, 93, 709-728.
PubMed ID: 17483174.

Maurya, M. R., and Subramaniam, S. (2007) A Kinetic Model for Calcium Dynamics in RAW 264.7 Cells: 2. Knockdown Response and Long-Term Response, Biophys J, 93, 729-740.
PubMed ID: 17483189.

Merrill, A. H., Jr., Wang, M. D., Park, M., and Sullards, M. C. (2007) (Glyco)sphingolipidology: an amazing challenge and opportunity for systems biology, Trends Biochem Sci, 32, 457-468.
PubMed ID: 17928229.

Murphy, R. C., James, P. F., McAnoy, A. M., Krank, J., Duchoslav, E., and Barkley, R. M. (2007) Detection of the abundance of diacylglycerol and triacylglycerol molecular species in cells using neutral loss mass spectrometry, Anal Biochem, 366, 59-70.
PubMed ID: 17442253.

Murphy, R. C., Fitzgerald, M., and Barkley, R. M. (2007) Neutral lipidomics and mass spectrometry, in Metabolomics, Metabonomics and Metabolite Profiling (Biomolecular Science series) (Griffiths, W. ed., RSC Publishing, London, 161-189.

Rao, R. P., Yuan, C., Allegood, J. C., Rawat, S. S., Edwards, M. B., Wang, X., Merrill, A. H., Jr., Acharya, U., and Acharya, J. K. (2007) Ceramide transfer protein function is essential for normal oxidative stress response and lifespan, Proc Natl Acad Sci U S A, 104, 11364-11369.
PubMed ID: 17592126.

Rouzer, C. A., Ivanova, P. T., Byrne, M. O., Brown, H. A., and Marnett, L. J. (2007) Lipid profiling reveals glycerophospholipid remodeling in zymosan-stimulated macrophages, Biochemistry, 46, 6026-6042.
PubMed ID: 17458939.

Sparagna, G. C., Chicco, A. J., Murphy, R. C., Bristow, M. R., Johnson, C. A., Rees, M. L., Maxey, M. L., McCune, S. A., and Moore, R. L. (2007) Loss of cardiac tetralinoleoyl cardiolipin in human and experimental heart failure, J Lipid Res, 48, 1559-1570.
PubMed ID: 17426348.

Sud, M., Fahy, E., Cotter, D., Brown, A., Dennis, E. A., Glass, C. K., Merrill, A. H., Jr., Murphy, R. C., Raetz, C. R., Russell, D. W., and Subramaniam, S. (2007) LMSD: LIPID MAPS structure database, Nucleic Acids Res, 35, D527-532.
PubMed ID: 17098933.

Surviladze, Z., Harrison, K. A., Murphy, R. C., and Wilson, B. S. (2007) FcepsilonRI and Thy-1 domains have unique protein and lipid compositions, J Lipid Res, 48, 1325-1335.
PubMed ID: 17387221.

Thomas, M. C., Mitchell, T. W., Harman, D. G., Deeley, J. M., Murphy, R. C., and Blanksby, S. J. (2007) Elucidation of Double Bond Position in Unsaturated Lipids by Ozone Electrospray Ionization Mass Spectrometry, Anal Chem, 79, 5013-5022.
PubMed ID: 17547368.

Urs, A. N., Dammer, E., Kelly, S., Wang, E., Merrill, A. H., Jr., and Sewer, M. B. (2007) Steroidogenic factor-1 is a sphingolipid binding protein, Mol Cell Endocrinol, 265-266, 174-178.
PubMed ID: 17196738.

Wang, X., Ribeiro, A. A., Guan, Z., Abraham, S. N., and Raetz, C. R. (2007) Attenuated virulence of a Francisella mutant lacking the lipid A 4'-phosphatase, Proc Natl Acad Sci U S A, 104, 4136-4141.
PubMed ID: 17360489.

Ward, W. C., Guan, Z., Zucca, F. A., Fariello, R. G., Kordestani, R., Zecca, L., Raetz, C. R., and Simon, J. D. (2007) Identification and quantification of dolichol and dolichoic acid in neuromelanin from substantia nigra of the human brain, J Lipid Res, 48, 1457-1462.
PubMed ID: 17446624.

Yan, A., Guan, Z., and Raetz, C. R. (2007) An undecaprenyl phosphate-aminoarabinose flippase required for polymyxin resistance in Escherichia coli, J Biol Chem, 282, 36077-36089.
PubMed ID: 17928292

2006

Chiba, H., Piboonpocanun, S., Mitsuzawa, H., Kuronuma, K., Murphy, R. C., and Voelker, D. R. (2006) Pulmonary surfactant proteins and lipids as modulators of inflammation and innate immunity, Respirology, 11 Suppl, S2-6.
PubMed ID: 16423264.

Cotter, D., Maer, A., Guda, C., Saunders, B., and Subramaniam, S. (2006) LMPD: LIPID MAPS proteome database, Nucleic Acids Res, 34, D507-510.
PubMed ID: 16381922.

Cummins, C. L., Volle, D. H., Zhang, Y., McDonald, J. G., Sion, B., Lefrancois-Martinez, A. M., Caira, F., Veyssiere, G., Mangelsdorf, D. J., and Lobaccaro, J. M. (2006) Liver X receptors regulate adrenal cholesterol balance, J Clin Invest, 116, 1902-1912.
PubMed ID: 16823488.

Dragusin, M., Wehner, S., Kelly, S., Wang, E., Merrill, A. H., Jr., Kalff, J. C., and van Echten-Deckert, G. (2006) Effects of sphingosine-1-phosphate and ceramide-1-phosphate on rat intestinal smooth muscle cells: implications for postoperative ileus, FASEB J, 20, 1930-1932.
PubMed ID: 16877527.

Giussani, P., Maceyka, M., Le Stunff, H., Mikami, A., Lepine, S., Wang, E., Kelly, S., Merrill, A. H., Jr., Milstien, S., and Spiegel, S. (2006) Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide, Mol Cell Biol, 26, 5055-5069.
PubMed ID: 16782891.

Glass, C. K., and Ogawa, S. (2006) Combinatorial roles of nuclear receptors in inflammation and immunity, Nat Rev Immunol, 6, 44-55.
PubMed ID: 16493426.

Glass, C. K. (2006) Going nuclear in metabolic and cardiovascular disease, J Clin Invest, 116, 556-560.
PubMed ID: 16511587.

Gould, T. A., Herman, J., Krank, J., Murphy, R. C., and Churchill, M. E. (2006) Specificity of acyl-homoserine lactone synthases examined by mass spectrometry, J Bacteriol, 188, 773-783.
PubMed ID: 16385066.

Kanjilal-Kolar, S., and Raetz, C. R. (2006) Dodecaprenyl phosphate-galacturonic acid as a donor substrate for lipopolysaccharide core glycosylation in Rhizobium leguminosarum, J Biol Chem, 281, 12879-12887.
PubMed ID: 16497671.

Kanjilal-Kolar, S., Basu, S. S., Kanipes, M. I., Guan, Z., Garrett, T. A., and Raetz, C. R. (2006) Expression cloning of three Rhizobium leguminosarum lipopolysaccharide core galacturonosyltransferases, J Biol Chem, 281, 12865-12878.
PubMed ID: 16497674.

Kirwan, J. P., Gould, T. A., Schweizer, H. P., Bearden, S. W., Murphy, R. C., and Churchill, M. E. (2006) Quorum-sensing signal synthesis by the Yersinia pestis acyl-homoserine lactone synthase YspI, J Bacteriol, 188, 784-788.
PubMed ID: 16385067.

Linn, S. C., Andras, L. M., Kim, H. S., Wei, J., Nagiec, M. M., Dickson, R. C., and Merrill, A. H., Jr. (2006) Functional characterization of the promoter for the mouse SPTLC2 gene, which encodes subunit 2 of serine palmitoyltransferase, FEBS Lett, 580, 6217-6223.
PubMed ID: 17070807.

Milne, S., Ivanova, P., Forrester, J., and Alex Brown, H. (2006) Lipidomics: an analysis of cellular lipids by ESI-MS, Methods, 39, 92-103.
PubMed ID: 16846739.

Murphy, R. C., Krank, J., and Barkley, R. M. (2006) LC/MS methodology in lipid analysis and structural characterization of novel lipid species. in Functional Lipidomics (Feng, L., and Prestwich, G. eds.), CRC Press/Taylor & Francis Group, Boca Raton, FL, 17-55.

Raetz, C. R., Garrett, T. A., Reynolds, C. M., Shaw, W. A., Moore, J. D., Smith, D. C., Jr., Ribeiro, A. A., Murphy, R. C., Ulevitch, R. J., Fearns, C., Reichart, D., Glass, C. K., Benner, C., Subramaniam, S., Harkewicz, R., Bowers-Gentry, R. C., Buczynski, M. W., Cooper, J. A., Deems, R. A., and Dennis, E. A. (2006) Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4, J Lipid Res, 47, 1097-1111.
PubMed ID: 16479018.

Rittershaus, P. C., Kechichian, T. B., Allegood, J. C., Merrill, A. H., Jr., Hennig, M., Luberto, C., and Del Poeta, M. (2006) Glucosylceramide synthase is an essential regulator of pathogenicity of Cryptococcus neoformans, J Clin Invest, 116, 1651-1659.
PubMed ID: 16741577.

Rouzer, C. A., Ivanova, P. T., Byrne, M. O., Milne, S. B., Marnett, L. J., and Brown, H. A. (2006) Lipid profiling reveals arachidonate deficiency in RAW264.7 cells: Structural and functional implications, Biochemistry, 45, 14795-14808.
PubMed ID: 17144673.

Schaaf, G., Betts, L., Garrett, T. A., Raetz, C. R., and Bankaitis, V. A. (2006) Crystallization and preliminary X-ray diffraction analysis of phospholipid-bound Sfh1p, a member of the Saccharomyces cerevisiae Sec14p-like phosphatidylinositol transfer protein family, Acta Crystallograph Sect F Struct Biol Cryst Commun, 62, 1156-1160.
PubMed ID: 17077504.

Wang, X., Ribeiro, A. A., Guan, Z., McGrath, S. C., Cotter, R. J., and Raetz, C. R. (2006) Structure and biosynthesis of free lipid A molecules that replace lipopolysaccharide in Francisella tularensis subsp. novicida, Biochemistry, 45, 14427-14440.
PubMed ID: 17128982.

Yang, C., McDonald, J. G., Patel, A., Zhang, Y., Umetani, M., Xu, F., Westover, E. J., Covey, D. F., Mangelsdorf, D. J., Cohen, J. C., and Hobbs, H. H. (2006) Sterol intermediates from cholesterol biosynthetic pathway as liver X receptor ligands, J Biol Chem, 281, 27816-27826.
PubMed ID: 16857673.

Yildiz, Y., Matern, H., Thompson, B., Allegood, J. C., Warren, R. L., Ramirez, D. M., Hammer, R. E., Hamra, F. K., Matern, S., and Russell, D. W. (2006) Mutation of beta-glucosidase 2 causes glycolipid storage disease and impaired male fertility, J Clin Invest, 116, 2985-2994.
PubMed ID: 17080196.

Zemski Berry, K. A., and Murphy, R. C. (2006) Analysis of polyunsaturated aminophospholipid molecular species using isotope-tagged derivatives and tandem mass spectrometry/mass spectrometry/mass spectrometry, Anal Biochem, 349, 118-128.
PubMed ID: 16384548.

Zheng, W., Kollmeyer, J., Symolon, H., Momin, A., Munter, E., Wang, E., Kelly, S., Allegood, J. C., Liu, Y., Peng, Q., Ramaraju, H., Sullards, M. C., Cabot, M., and Merrill, A. H., Jr. (2006) Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy, Biochim Biophys Acta, 1758, 1864-1884.
PubMed ID: 17052686.

2005

Dennis, E. A., Brown, H. A., Deems, R. A., Glass, C. K., Merrill, A. H., Jr., Murphy, R. C., Raetz, C. R., Shaw, W., Subramaniam, S., Russell, D. W., vanNieuwenhze, M. S., White, S. H., Witztum, J. L., and Wooley, J. (2005) The LIPID MAPS approach to lipidomics. in Functional Lipidomics (Feng, L., and Prestwich, G. eds.), CRC Press/Taylor & Francis Group, Boca Raton, FL, 1-15.

Fahy, E., Subramaniam, S., Brown, H. A., Glass, C. K., Merrill, A. H., Jr., Murphy, R. C., Raetz, C. R., Russell, D. W., Seyama, Y., Shaw, W., Shimizu, T., Spener, F., van Meer, G., VanNieuwenhze, M. S., White, S. H., Witztum, J. L., and Dennis, E. A. (2005) A comprehensive classification system for lipids, J Lipid Res, 46, 839-861.
PubMed ID: 15722563.

Guan, Z., Breazeale, S. D., and Raetz, C. R. (2005) Extraction and identification by mass spectrometry of undecaprenyl diphosphate-MurNAc-pentapeptide-GlcNAc from Escherichia coli, Anal Biochem, 345, 336-339.
PubMed ID: 16118008.

Hsiao, A., Ideker, T., Olefsky, J. M., and Subramaniam, S. (2005) VAMPIRE microarray suite: a web-based platform for the interpretation of gene expression data, Nucleic Acids Res, 33, W627-632.
PubMed ID: 15980550.

Inagaki, T., Choi, M., Moschetta, A., Peng, L., Cummins, C. L., McDonald, J. G., Luo, G., Jones, S. A., Goodwin, B., Richardson, J. A., Gerard, R. D., Repa, J. J., Mangelsdorf, D. J., and Kliewer, S. A. (2005) Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis, Cell Metab, 2, 217-225.
PubMed ID: 16213224.

Maceyka, M., Sankala, H., Hait, N. C., Le Stunff, H., Liu, H., Toman, R., Collier, C., Zhang, M., Satin, L. S., Merrill, A. H., Jr., Milstien, S., and Spiegel, S. (2005) SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism, J Biol Chem, 280, 37118-37129.
PubMed ID: 16118219.

McAnoy, A. M., Wu, C. C., and Murphy, R. C. (2005) Direct qualitative analysis of triacylglycerols by electrospray mass spectrometry using a linear ion trap, J Am Soc Mass Spectrom, 16, 1498-1509.
PubMed ID: 16019221.

McClerren, A. L., Endsley, S., Bowman, J. L., Andersen, N. H., Guan, Z., Rudolph, J., and Raetz, C. R. (2005) A slow, tight-binding inhibitor of the zinc-dependent deacetylase LpxC of lipid A biosynthesis with antibiotic activity comparable to ciprofloxacin, Biochemistry, 44, 16574-16583.
PubMed ID: 16342948.

Merrill, A. H., Jr., Sullards, M. C., Allegood, J. C., Kelly, S., and Wang, E. (2005) Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry, Methods, 36, 207-224.
PubMed ID: 15894491.

Milne, S. B., Ivanova, P. T., DeCamp, D., Hsueh, R. C., and Brown, H. A. (2005) A targeted mass spectrometric analysis of phosphatidylinositol phosphate species, J Lipid Res, 46, 1796-1802.
PubMed ID: 15897608.

Murphy, R. C., Barkley, R. M., Zemski Berry, K., Hankin, J., Harrison, K., Johnson, C., Krank, J., McAnoy, A., Uhlson, C., and Zarini, S. (2005) Electrospray ionization and tandem mass spectrometry of eicosanoids, Anal Biochem, 346, 1-42.
PubMed ID: 15961057.

Murphy, R. C., Raetz, C. R., Reynolds, C. M., and Barkley, R. M. (2005) Mass spectrometry advances in lipidomica: collision-induced decomposition of Kdo2-lipid A, Prostaglandins Other Lipid Mediat, 77, 131-140.
PubMed ID: 16099398.

Ogawa, S., Lozach, J., Benner, C., Pascual, G., Tangirala, R. K., Westin, S., Hoffmann, A., Subramaniam, S., David, M., Rosenfeld, M. G., and Glass, C. K. (2005) Molecular determinants of crosstalk between nuclear receptors and toll-like receptors, Cell, 122, 707-721.
PubMed ID: 16143103.

Ortlund, E. A., Lee, Y., Solomon, I. H., Hager, J. M., Safi, R., Choi, Y., Guan, Z., Tripathy, A., Raetz, C. R., McDonnell, D. P., Moore, D. D., and Redinbo, M. R. (2005) Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP, Nat Struct Mol Biol, 12, 357-363.
PubMed ID: 15723037.

Papin, J. A., Hunter, T., Palsson, B. O., and Subramaniam, S. (2005) Reconstruction of cellular signalling networks and analysis of their properties, Nat Rev Mol Cell Biol, 6, 99-111.
PubMed ID: 15654321.

Sparagna, G. C., Johnson, C. A., McCune, S. A., Moore, R. L., and Murphy, R. C. (2005) Quantitation of cardiolipin molecular species in spontaneously hypertensive heart failure rats using electrospray ionization mass spectrometry, J Lipid Res, 46, 1196-1204.
PubMed ID: 15772420.

Sullards, M. C., and Merrill, A. H., Jr. (2005) Liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis of sphingolipids in lipidomics. in Functional Lipidomics (Feng, L., and Prestwich, G. eds.), CRC Press/Taylor & Francis Group, Boca Raton, FL, 159-187.

Zemski Berry, K. A., and Murphy, R. C. (2005) Analysis of cell membrane aminophospholipids as isotope-tagged derivatives, J Lipid Res, 46, 1038-1046.
PubMed ID: 15716579.

2004

Choi, J. Y., Martin, W. E., Murphy, R. C., and Voelker, D. R. (2004) Phosphatidylcholine and N-methylated phospholipids are nonessential in Saccharomyces cerevisiae, J Biol Chem, 279, 42321-42330.
PubMed ID: 15269223.

Monick, M. M., Mallampalli, R. K., Bradford, M., McCoy, D., Gross, T. J., Flaherty, D. M., Powers, L. S., Cameron, K., Kelly, S., Merrill, A. H., Jr., and Hunninghake, G. W. (2004) Cooperative prosurvival activity by ERK and Akt in human alveolar macrophages is dependent on high levels of acid ceramidase activity, J Immunol, 173, 123-135.
PubMed ID: 15210766.

Quittnat, F., Nishikawa, Y., Stedman, T. T., Voelker, D. R., Choi, J. Y., Zahn, M. M., Murphy, R. C., Barkley, R. M., Pypaert, M., Joiner, K. A., and Coppens, I. (2004) On the biogenesis of lipid bodies in ancient eukaryotes: synthesis of triacylglycerols by a Toxoplasma DGAT1-related enzyme, Mol Biochem Parasitol, 138, 107-122.
PubMed ID: 15500922.

2003

Pulfer, M., and Murphy, R. C. (2003) Electrospray mass spectrometry of phospholipids, Mass Spectrom Rev, 22, 332-364.
PubMed ID: 12949918.

Collaborative Works

M. T. Audrey Nguyen, Svetlana Favelyukis, Anh-Khoi Nguyen, Donna Reichart, Peter A. Scott, Alan Jenn, Ru Liu-Bryan, Christopher K. Glass, Jaap G. Neels, and Jerrold M. Olefsky (2007) A Subpopulation of Macrophages Infiltrates Hypertrophic Adipose Tissue and Is Activated by Free Fatty Acids via Toll-like Receptors 2 and 4 and JNK-dependent Pathways J. Biol. Chem Vol. 282, Issue 48, 35279-35292.
PubMed ID: 17916553

Pradervand S, Maurya MR, Subramaniam S. (2006) Identification of signaling components required for the prediction of cytokine release in RAW 264.7 macrophages Genome Biology, 7:R11.
PubMed ID: 16507166