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Analysis of Foam Cells

Foam cell Study +/- LDL Receptor, Normal diet/High-fat diet

Peritoneal macrophages were obtained from thioglycolate-stimulated wild-type and low-density lipoprotein receptor knockout (LDLR(-/-)) mice maintained on normal and Western (High-fat, high cholesterol) diets according to protocols PP0000003000 and PP0000003100 (pdf). MS measurements were taken for: (i) Wild-type mouse/Normal diet; (ii) Wild-type mouse/High-cholesterol diet; (iii)LDLR(-/-) mouse/Normal diet; (iv) LDLR( -/-) mouse/High-cholesterol diet. Three separate experiments (biological replicates) were carried out, and MS measurements were performed in triplicate (technical replicates).

Browse Averages of replicates, by analyte category (FA) Eicosanoids [media] (Expt BCJ070122) (FA) Eicosanoids [media] (Expt BCJ070123) (FA) Eicosanoids [media] (Expt BCJ070124) (FA) Fatty acids [cells] (Expt BCJ070122) (FA) Fatty acids [cells] (Expt BCJ070123) (FA) Fatty acids [cells] (Expt BCJ070124) (ST) Sterol Lipids (Expt BCJ070122) (ST) Sterol Lipids (Expt BCJ070123) (ST) Sterol Lipids (Expt BCJ070124) (ST) Cholesteryl Esters (Expt BCJ070122) (ST) Cholesteryl Esters (Expt BCJ070123) (ST) Cholesteryl Esters (Expt BCJ070124) (SP) Sphingolipids (Expt BCJ070122) (SP) Sphingolipids (Expt BCJ070123) (SP) Sphingolipids (Expt BCJ070124) (GP) Glycerophospholipids (Expt BCJ070122) (GP) Glycerophospholipids (Expt BCJ070123) (GP) Cardiolipins (Expt BCJ070122) (GP) Cardiolipins (Expt BCJ070123) (GP) Cardiolipins (Expt BCJ070124) (PR) Prenol Lipids (Expt BCJ070122) (PR) Prenol Lipids (Expt BCJ070123) (PR) Prenol Lipids (Expt BCJ070124)